SCHEMBL525334

SCHEMBL525334

O=C(N=S(=O)=O)Nc1ncccn1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.46
HTT P42858 1/20 0.46
ALDH1A1 P00352 3/20 0.41
KDM4E B2RXH2 2/20 0.40
GAA P10253 2/20 0.40
EPHX2 P34913 1/20 0.38
MAPT P10636 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
RAB9A P51151 2/20 0.36
FFAR2 O15552 1/20 0.36
NPC1 O15118 1/20 0.35
PKM P14618 1/20 0.35
MEN1 O00255 1/20 0.35
USP2 O75604 1/20 0.35
GLA P06280 1/20 0.35
KMT2A Q03164 1/20 0.35
RXFP1 Q9HBX9 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9603354 0.82 EPHX2 (0.39) EPHX2
SCHEMBL4564658 0.77 RAB9A (0.61) LMNAKDM4EGAARAB9ANPC1
SCHEMBL10571586 0.76 MEN1 (0.39) LMNAHTTALDH1A1KDM4EMAPT
SCHEMBL23566413 0.72 LMNA (0.56) LMNAHTTALDH1A1KDM4EGAA
SCHEMBL10565228 0.71 SMN1; SMN2 (0.41) KDM4EMAPTRAB9ANPC1KMT2A
SCHEMBL29268541 0.71 PTGS2 (0.36) HTTPKM
SCHEMBL4303429 0.70 LMNA (0.54) LMNAHTTALDH1A1KDM4EGAA
Propene SCHEMBL11084085 0.70 LMNA (0.38) LMNAHTTALDH1A1KDM4ERAB9A
SCHEMBL7081771 0.69 NPC1 (0.50) LMNAHTTALDH1A1MAPTRAB9A
SCHEMBL3808864 0.69 LMNA (0.52) LMNAHTTALDH1A1KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105473721-A Methods and compositions employing a sulfonylurea-dependent stabilization domain PIONEER HI BRED INT 2016-04-06 CN claimed
CN-105473722-A Methods and compositions to improve the spread of chemical signals in plants PIONEER HI BRED INT 2016-04-06 CN claimed
US-4685961-A CEREAL CROPS CIBA-GEIGY CORPORATION (US) 1987-08-11 US claimed
EP-4258878-B1 HERBICIDE COMPOSITION UPL CORPORATION LTD (MU) 2025-02-19 EP disclosed
WO-2024110852-A1 A HERBICIDAL COMPOSITION AND A PROCESS FOR PREPARING THE SAME THEREOF UPL LIMITED (IN) 2024-05-30 WO disclosed
US-20240049712-A1 HERBICIDE COMPOSITION UPL CORPORATION LTD (MU) 2024-02-15 US disclosed
CN-117099786-A Substituted 3, 4-dihydropyrimidin-2 (1H) -ones as seed treatment agents 阿达玛马克西姆股份有限公司 2023-11-24 CN disclosed
WO-2023209346-A1 HERBICIDE COMBINATIONS, COMPOSITION AND METHOD FOR CONTROLLING HARMFUL PLANTS UPL MAURITIUS LIMITED (MU) 2023-11-02 WO disclosed
EP-4258878-A1 HERBICIDE COMPOSITION UPL Corporation Limited (MU) 2023-10-18 EP disclosed
WO-2022148949-A1 HERBICIDE COMPOSITION UPL Corporation Limited (MU) 2022-07-14 WO disclosed
CN-113573585-A Stable herbicide formulation of pyrazosulfuron-ethyl UPL有限公司 2021-10-29 CN disclosed
US-4940792-A Herbicidal sulfonylureas CIBA-GEIGY CORPORATION (US) 1990-07-10 US disclosed
US-4940792-A Herbicidal sulfonylureas CIBA-GEIGY CORPORATION (US) 1990-07-10 US disclosed
US-4764203-A Herbicidal sulfonylureas CIBA-GEIGY CORPORATION (US) 1988-08-16 US disclosed
US-4764203-A Herbicidal sulfonylureas CIBA-GEIGY CORPORATION (US) 1988-08-16 US disclosed
US-4741760-A Pyrimidine derivatives having a herbicidal action and an action regulating plant growth CIBA-GEIGY CORPORATION (US) 1988-05-03 US disclosed
US-4685961-A CEREAL CROPS CIBA-GEIGY CORPORATION (US) 1987-08-11 US disclosed
US-4685961-A CEREAL CROPS CIBA-GEIGY CORPORATION (US) 1987-08-11 US disclosed
EP-0084224-B1 HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-10-08 EP disclosed
EP-0084224-A1 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-07-27 EP disclosed