Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.61 |
| ▸ | NPC1 | O15118 | 7/20 | 0.61 |
| ▸ | PKM | P14618 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 1/20 | 0.53 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.53 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1486005 | 0.80 | NPC1 (0.63) | RAB9ANPC1PKMGAAMEN1 | |
| SCHEMBL10604839 | 0.77 | CHRNB2 (0.46) | RAB9ANPC1PKMLMNA | |
| SCHEMBL525334 | 0.77 | LMNA (0.46) | RAB9ANPC1PKMGAAMEN1 | |
| SCHEMBL9750118 | 0.77 | NPC1 (0.81) | RAB9ANPC1PKMGAAMEN1 | |
| SCHEMBL30565139 | 0.77 | RAB9A (1.00) | RAB9ANPC1PKMGAAMEN1 | |
| SCHEMBL25857032 | 0.76 | RAB9A (0.58) | RAB9ANPC1PKMGAAMEN1 | |
| SCHEMBL519066 | 0.75 | RAB9A (0.73) | RAB9ANPC1PKMGAAMEN1 | |
| SCHEMBL3078691 | 0.75 | RAB9A (0.73) | RAB9ANPC1PKMGAAMEN1 | |
| SCHEMBL9028468 | 0.73 | RAB9A (0.70) | RAB9ANPC1PKMGAAMEN1 | |
| SCHEMBL6879467 | 0.73 | RAB9A (0.70) | RAB9ANPC1PKMGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101903379-A | Herbicidal compound based on N-azine group-N '-pyridyl sulfonylurea | BAYER CROPSCIENCE AG | 2010-12-01 | — | — | CN | claimed |
| US-12048677-B2 | Compositions and uses thereof for the treatment of heart failure in domestic animals | CEVA SANTE ANIMALE (FR) | 2024-07-30 | — | — | US | disclosed |
| US-11666587-B2 | Veterinary composition comprising torasemide for the treatment of pulmonary edema associated with heart failure in domestic animals | CEVA SANTE ANIMALE (FR) | 2023-06-06 | — | — | US | disclosed |
| US-20200206162-A1 | COMPOSITIONS AND USES THEREOF FOR THE TREATMENT OF HEART FAILURE IN DOMESTIC ANIMALS | CEVA SANTE ANIMALE (FR) | 2020-07-02 | — | — | US | disclosed |
| US-20180221394-A1 | VETERINARY COMPOSITION COMPRISING TORASEMIDE FOR THE TREATMENT OF PULMONARY EDEMA ASSOCIATED WITH HEART FAILURE IN DOMESTIC ANIMALS | CEVA SANTE ANIMALE (FR) | 2018-08-09 | — | — | US | disclosed |
| CN-105248428-B | Herbicide combinations comprising a herbicide of the class of the diaminos-triazines | 拜耳知识产权有限责任公司 | 2017-11-14 | — | — | CN | disclosed |
| EP-3229841-A1 | VETERINARY COMPOSITION COMPRISING TORASEMIDE FOR THE TREATMENT OF PULMONARY EDEMA ASSOCIATED WITH HEART FAILURE IN DOMESTIC ANIMALS | Ceva Sante Animale (FR) | 2017-10-18 | — | — | EP | disclosed |
| WO-2016092060-A1 | VETERINARY COMPOSITION COMPRISING TORASEMIDE FOR THE TREATMENT OF PULMONARY EDEMA ASSOCIATED WITH HEART FAILURE IN DOMESTIC ANIMALS | CEVA SANTE ANIMALE (FR) | 2016-06-16 | — | — | WO | disclosed |
| EP-3031471-A1 | Veterinary composition for the treatment of pulmonary edema associated with heart failure in domestic animals | Ceva Sante Animale (FR) | 2016-06-15 | — | — | EP | disclosed |
| CN-105248428-A | Herbicide combinations comprising a herbicide of the class of the diaminos-triazines | BAYER CROPSCIENCE AG | 2016-01-20 | — | — | CN | disclosed |
| CN-101903379-A | Herbicidal compound based on N-azine group-N '-pyridyl sulfonylurea | BAYER CROPSCIENCE AG | 2010-12-01 | — | — | CN | disclosed |
| EP-1898705-B1 | OIL SUSPENSION CONCENTRATE | BAYER CROPSCIENCE AG (DE) | 2009-10-14 | — | — | EP | disclosed |
| CN-101517084-A | Acetolactate synthase (ALS) selectable marker from trichoderma reesei | DANISCO US INC (US) | 2009-08-26 | — | — | CN | disclosed |
| CN-100413848-C | Acylsulfamoylbenzamides, crop protection compositions containing them and processes for their preparation | HOECHST SCHERING AGREVO GMBH (DE) | 2008-08-27 | — | — | CN | disclosed |
| EP-1898705-A1 | OIL SUSPENSION CONCENTRATE | Bayer CropScience AG (DE) | 2008-03-19 | — | — | EP | disclosed |
| WO-2006131187-A1 | OIL SUSPENSION CONCENTRATE | BAYER CROPSCIENCE AG (DE) | 2006-12-14 | — | — | WO | disclosed |
| CN-1829441-A | Liquid formulation | BAYER CROPSCIENCE GMBH (DE) | 2006-09-06 | — | — | CN | disclosed |
| CN-1092189-C | Substituted isoxazolines, process for producing them, agents containing them and their use as safeners | HOECHEST SCHERING AGREVO GMBH (DE) | 2002-10-09 | — | — | CN | disclosed |
| CN-1133038-A | Substituted isoxazolines, process for producing them, agents containing them and their use as safeners | HOECHST SCHERING AGREVO GMBH (DE) | 1996-10-09 | — | — | CN | disclosed |
| CN-1053236-A | Pyridine sulfonylurea weedicide and plant-growth regulator, their preparation method and application | HOECHST AG (DE) | 1991-07-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180221394-A1 | VETERINARY COMPOSITION COMPRISING TORASEMIDE FOR THE TREATMENT OF PULMONARY EDEMA ASSOCIATED WITH HEART FAILURE IN DOMESTIC ANIMALS | TNNI3, TNNT2, PIGS | RAB9A 503/4885NPC1 4212/4885PKM 1428/4885 |
| US-20200206162-A1 | COMPOSITIONS AND USES THEREOF FOR THE TREATMENT OF HEART FAILURE IN DOMESTIC ANIMALS | TNNI3, TNNT2, PIGS | RAB9A 798/4885NPC1 4395/4885PKM 1334/4885 |
| US-12048677-B2 | Compositions and uses thereof for the treatment of heart failure in domestic animals | TNNI3, TNNT2, PIGS | RAB9A 798/4885NPC1 4395/4885PKM 1334/4885 |
| US-11666587-B2 | Veterinary composition comprising torasemide for the treatment of pulmonary edema associated with heart failure in domestic animals | TNNI3, TNNT2, PIGS | RAB9A 503/4885NPC1 4212/4885PKM 1428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.