SCHEMBL5256014

SCHEMBL5256014

CC(C(C[Al](CC(c1ccccc1)C(C)S(C)(=O)=O)CC(c1ccccc1)C(C)S(C)(=O)=O)c1ccccc1)S(C)(=O)=O

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.40
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 1/20 0.38
GMNN O75496 1/20 0.38
LMNA P02545 1/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
PMP22 Q01453 1/20 0.38
KMT2A Q03164 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
TRPA1 O75762 2/20 0.34
CYP2C19 P33261 2/20 0.33
KCNA5 P22460 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL335664 0.77 TAAR1 (0.59) TAAR1LMNAKMT2ACYP2C19CYP3A4
SCHEMBL5775899 0.75 MMP1 (0.37) TAAR1ALDH1A1KDM4EGMNNLMNA
SCHEMBL2020687 0.69 ALDH1A1 (0.44) TAAR1ALDH1A1KDM4EGMNNLMNA
SCHEMBL17084181 0.68 TAAR1 (0.53) TAAR1ALDH1A1KDM4EGMNNLMNA
SCHEMBL335496 0.68 TAAR1 (0.56) TAAR1ALDH1A1KDM4ELMNAKMT2A
SCHEMBL5989826 0.68
SCHEMBL13999543 0.67 HKDC1 (0.44) TAAR1ALDH1A1KDM4EGMNNLMNA
SCHEMBL6905050 0.67 TAAR1 (0.47) TAAR1LMNAKMT2ATRPA1CYP2D6
SCHEMBL5555050 0.66 SRC (0.39) ALDH1A1KDM4EGMNNLMNAPOLB
SCHEMBL935224 0.66 CES2 (0.43) TAAR1ALDH1A1KDM4EGMNNLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1753792-A1 PROCESS FOR THE PREPARATION OF ATACTIC 1-BUTENE POLYMERS Basell Polyolefine GmbH (DE) 2007-02-21 EP disclosed
WO-2005105865-A1 PROCESS FOR THE PREPARATION OF ATACTIC 1-BUTENE POLYMERS BASELL POLYOLEFINE GMBH (DE) 2005-11-10 WO disclosed