Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 10/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.38 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.37 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5260594 | 0.88 | RAB9A (0.44) | KMT2AUTS2RCYP24A1MEN1RAB9A | |
| SCHEMBL5262363 | 0.81 | P2RX7 (0.40) | KMT2AMEN1RAB9ASMN1; SMN2GPR139 | |
| SCHEMBL5260356 | 0.81 | CNR1 (0.52) | UTS2R | |
| SCHEMBL5264039 | 0.80 | KMT2A (0.53) | KMT2AGAAHSD17B10MEN1USP36 | |
| SCHEMBL5260607 | 0.77 | TGFBR1 (0.34) | KMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL5262774 | 0.76 | SLC6A9 (0.54) | KMT2AGAAHSD17B10UTS2RMEN1 | |
| SCHEMBL5266049 | 0.74 | RAB9A (0.60) | KMT2AMEN1RAB9ASMN1; SMN2GPR139 | |
| SCHEMBL5260012 | 0.74 | UTS2R (0.53) | KMT2AUTS2RCYP24A1MEN1RAB9A | |
| SCHEMBL5263559 | 0.73 | RAB9A (0.50) | KMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL5262488 | 0.72 | SLC6A9 (0.55) | KMT2AUTS2RCYP24A1MEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494997-A4 | SUBSTITUTED ARYL AMIDES | MERCK & CO INC (US) | 2007-04-11 | — | — | EP | claimed |
| JP-2005527586-A | — | — | 2005-09-15 | — | — | JP | claimed |
| EP-1494997-A1 | SUBSTITUTED ARYL AMIDES | Merck & Co., Inc. (US) | 2005-01-12 | — | — | EP | claimed |
| WO-2003087037-A1 | SUBSTITUTED ARYL AMIDES | MERCK & CO., INC. (US) | 2003-10-23 | — | — | WO | claimed |
| EP-1494997-A4 | SUBSTITUTED ARYL AMIDES | MERCK & CO INC (US) | 2007-04-11 | — | — | EP | disclosed |
| EP-1494997-A1 | SUBSTITUTED ARYL AMIDES | Merck & Co., Inc. (US) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003087037-A1 | SUBSTITUTED ARYL AMIDES | MERCK & CO., INC. (US) | 2003-10-23 | — | — | WO | disclosed |