Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | IDH2 | P48735 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KIF11 | P52732 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28074110 | 0.98 | MAPT (0.55) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL2925587 | 0.84 | MAPT (0.58) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL394991 | 0.84 | KIF11 (0.70) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL29748950 | 0.84 | MAPT (0.58) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL23997779 | 0.80 | MAPT (0.55) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL125625 | 0.80 | ALDH1A1 (0.61) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL10985842 | 0.80 | MAPT (0.55) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL10494598 | 0.80 | MAPT (0.55) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL21979534 | 0.80 | MAPT (0.55) | MAPTALDH1A1GAANPSR1TDP1 | |
| SCHEMBL1921482 | 0.80 | KIF11 (0.70) | MAPTALDH1A1GAANPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106750257-B | A kind of heat-resisting polyarylether resin of high fluorinated volume and preparation method thereof | 吉林大学 | 2019-04-12 | — | — | CN | claimed |
| CN-106750257-A | A kind of heat-resisting polyarylether resin of fluorinated volume high and preparation method thereof | 吉林大学 | 2017-05-31 | — | — | CN | claimed |
| CN-103391935-B | Diaminopyrimidine derivatives and process for preparing same | Liu Hanyangxing (KR) | 2015-12-23 | — | — | CN | claimed |
| CN-104592116-A | 1,3,5-trisubstituted pyrazole compounds, and preparation method and application thereof | UNIV SHANDONG | 2015-05-06 | — | — | CN | claimed |
| CN-102143940-A | Cyclohexyl amide derivatives as CRF-1 receptor antagonists and uses thereof | NOVARTIS AG | 2011-08-03 | — | — | CN | claimed |
| EP-4313293-A1 | TETRAHYDROTHIENO PYRIDINE DERIVATIVES AS DDRS INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022200580-A1 | TETRAHYDROTHIENO PYRIDINE DERIVATIVES AS DDRS INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2022-09-29 | — | — | WO | disclosed |
| CN-106046030-B | The application of organic electronic device, dopant with dopant and method for manufacturing dopant | 欧司朗OLED股份有限公司 | 2019-07-16 | — | — | CN | disclosed |
| CN-109867676-A | Compound derived from a kind of pyrrolopyrimidine, pharmaceutical composition with and application thereof | 北京普祺医药科技有限公司 | 2019-06-11 | — | — | CN | disclosed |
| CN-107207515-B | Pyrazine compounds for the treatment of infectious diseases | 豪夫迈·罗氏有限公司 | 2019-05-28 | — | — | CN | disclosed |
| CN-109794293-A | A kind of application of iron-based photochemical catalyst and its rhodamine B degradation | 杭州师范大学 | 2019-05-24 | — | — | CN | disclosed |
| CN-106750257-B | A kind of heat-resisting polyarylether resin of high fluorinated volume and preparation method thereof | 吉林大学 | 2019-04-12 | — | — | CN | disclosed |
| EP-1765768-A1 | SUBSTITUTED ACIDS FOR THE TREATMENT OF RESPIRATORY DISEASES | AstraZeneca AB (SE) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006113089-A2 | DIAGNOSIS BY DETERMINATION OF HYPERACTIVITY OR INCREASED EXPRESSION OF MEMBERS OF CELL SIGNALING PATHWAYS | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2006-10-26 | — | — | WO | disclosed |
| WO-2006044823-A2 | HETEROARYL-SUBSTITUTED ALKYNE COMPOUNDS AND METHOD OF USE | AMGEN INC. (US) | 2006-04-27 | — | — | WO | disclosed |
| WO-2006005909-A1 | SUBSTITUTED ACIDS FOR THE TREATMENT OF RESPIRATORY DISEASES | ASTRAZENECA AB (SE) | 2006-01-19 | — | — | WO | disclosed |
| CN-1215041-C | Method for preparing polyhalogenated paratriefluoromethylanilines | AVENTIS CROPSCIENCE SA (FR) | 2005-08-17 | — | — | CN | disclosed |
| CN-1330625-A | Method for preparing polyhalogenated paratriefluoromethylanilines | AVENTIS CROPSCIENCE SA (FR) | 2002-01-09 | — | — | CN | disclosed |
| EP-0249885-A2 | Heat-sensitive recording material | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1987-12-23 | — | — | EP | disclosed |
| EP-0059975-B1 | THERMORESPONSIVE RECORDING SHEET | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1985-06-26 | — | — | EP | disclosed |