SCHEMBL526209

SCHEMBL526209

NC(=S)Nc1ccncc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.60
TP53 P04637 1/20 0.60
TYR P14679 1/20 0.60
TSHR P16473 1/20 0.60
TAS2R38 P59533 1/20 0.60
HSD17B10 Q99714 1/20 0.60
EPHX1 P07099 2/20 0.55
MDM2 Q00987 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2D6 P10635 1/20 0.54
CYP2C9 P11712 1/20 0.54
HPGD P15428 1/20 0.54
ALOX12 P18054 1/20 0.54
CYP2C19 P33261 1/20 0.54
KMT2A Q03164 2/20 0.50
KIF11 P52732 1/20 0.50
GAA P10253 1/20 0.50
MAPT P10636 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
KDM4E B2RXH2 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL31091389 0.98 ALDH1A1 (0.58) ALDH1A1TP53TYRTSHRTAS2R38
SCHEMBL1617015 0.87 KIF11 (0.62) ALDH1A1TP53TYRTSHRTAS2R38
SCHEMBL725810 0.82 ALDH1A1 (0.75) ALDH1A1TP53TYRTSHRTAS2R38
Methane SCHEMBL18335057 0.80 MDM2 (0.48) ALDH1A1TP53TYRTSHRTAS2R38
SCHEMBL9297614 0.78 MDM2 (0.56) ALDH1A1EPHX1MDM2KMT2AGAA
Phenylthiourea SCHEMBL28260094 0.77 ALDH1A1 (0.73) ALDH1A1TP53TYRTSHRTAS2R38
SCHEMBL1466506 0.76 MDM2 (0.54) ALDH1A1EPHX1MDM2KMT2AGAA
SCHEMBL230957 0.76 MDM2 (0.67) ALDH1A1EPHX1MDM2KMT2AKIF11
SCHEMBL160867 0.76 MDM2 (0.54) EPHX1MDM2KMT2AGAAMAPT
SCHEMBL222140 0.76 MDM2 (0.54) ALDH1A1EPHX1MDM2KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119776928-A Organic coordination environment rose gold electrolyte system and electrodeposition method 深圳市中天明晟科技有限公司 2025-04-08 CN claimed
CN-115449136-B Accelerator composition of rubber nanocomposite as well as preparation method and application thereof 浙江大学 2024-02-27 CN claimed
CN-115449136-A Accelerator composition of rubber nanocomposite and preparation method and application thereof 浙江大学 2022-12-09 CN claimed
CN-114864823-A Novel perovskite X-ray detector and preparation method thereof 中国科学院合肥物质科学研究院 2022-08-05 CN claimed
CN-110846011-B Carbon dioxide gel foam with thiourea structure and preparation method and application thereof 中国石油大学(华东) 2021-09-24 CN claimed
CN-110846011-A Carbon dioxide gel foam with thiourea structure and preparation method and application thereof 中国石油大学(华东) 2020-02-28 CN claimed
CN-109607592-A Transient metal sulfide/C-base composte material preparation method and applications of N doping 温州大学 2019-04-12 CN claimed
CN-103741181-B A kind of many coordination agents cyanide-free gold electroplating plating solution and electrogilding technique HARBIN INSTITUTE OF TECHNOLOGY (CN) 2016-01-27 CN claimed
CN-104607159-A Novel chelate fiber as well as preparation method and application thereof UNIV SOOCHOW 2015-05-13 CN claimed
CN-104233384-A Cyanide-free gold electroplating solution and electroplating process using same ZHU ZHONGLIANG 2014-12-24 CN claimed
CN-103741181-A Multi-coordination-agent cyanide-free electrogilding liquid and electrogilding process HARBIN INST OF TECHNOLOGY 2014-04-23 CN claimed
WO-2025219374-A1 COMPOSITIONS AND METHODS FOR POLISHING DIELECTRIC BASF SE (DE) 2025-10-23 WO disclosed
WO-2025081371-A1 HIGH PERFORMANCE FRACTURING FOAM AND RELATED METHODS SAUDI ARABIAN OIL COMPANY (SA) 2025-04-24 WO disclosed
CN-119776928-A Organic coordination environment rose gold electrolyte system and electrodeposition method 深圳市中天明晟科技有限公司 2025-04-08 CN disclosed
CN-115449136-B Accelerator composition of rubber nanocomposite as well as preparation method and application thereof 浙江大学 2024-02-27 CN disclosed
CN-1314890-A Cyanoguanidines as cell proliferation inhibitors LEO PHARM PROD LTD (DK) 2001-09-26 CN disclosed
CN-1258279-A Cyanoguanidines as cell proliferation inhibitors LEO PHARM PROD LTD (DK) 2000-06-28 CN disclosed
US-4735957-A ANTIULCER AGENTS, CARDIOTONIC AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-04-05 US disclosed
US-4649146-A ANTIULCER FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1987-03-10 US disclosed
EP-0117082-A2 Thiazole derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-08-29 EP disclosed