Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL187133 | 0.86 | HCAR2 (0.54) | HCAR2MEN1HTTGFERKMT2A | |
| Pyrrole SCHEMBL5465677 | 0.79 | HCAR2 (0.71) | HCAR2MEN1KMT2AHSD17B10TBXA2R | |
| SCHEMBL1921878 | 0.71 | LMNA (0.46) | HCAR2MEN1KMT2AHSD17B10 | |
| SCHEMBL28029118 | 0.70 | LMNA (0.45) | HCAR2MEN1KMT2AHSD17B10 | |
| Pyrrole SCHEMBL5264669 | 0.69 | P2RX7 (0.37) | MEN1HTTGFERKMT2ATBXA2R | |
| SCHEMBL686904 | 0.69 | KMT2A (0.40) | MEN1HTTGFERKMT2AHSD17B10 | |
| Methylamine SCHEMBL27659540 | 0.68 | LMNA (0.43) | HCAR2MEN1KMT2AHSD17B10CYP19A1 | |
| SCHEMBL25220465 | 0.68 | KMT2A (0.53) | HCAR2MEN1KMT2AHSD17B10BCAT2 | |
| SCHEMBL9978366 | 0.67 | MEN1 (0.46) | HCAR2MEN1KMT2ABCAT2 | |
| SCHEMBL31123876 | 0.67 | KMT2A (0.56) | HCAR2MEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771448-A1 | AZAINDOLE CARBOXAMIDES | SCHWARZ PHARMA AG (DE) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006050976-A1 | AZAINDOLE CARBOXAMIDES | SCHWARZ PHARMA AG (DE) | 2006-05-18 | — | — | WO | disclosed |