Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DDO | Q99489 | 1/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL106575 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL6741706 | 0.82 | HCAR2 (0.94) | HCAR2ALDH1A1APPGAAHCAR3 | |
| Lithium SCHEMBL30194865 | 0.82 | HCAR2 (0.94) | HCAR2ALDH1A1APPGAAHCAR3 | |
| SCHEMBL27550564 | 0.82 | HCAR2 (0.94) | HCAR2ALDH1A1APPGAAHCAR3 | |
| Formaldehyde SCHEMBL28203822 | 0.80 | HCAR2 (0.90) | HCAR2ALDH1A1APPGAAHCAR3 | |
| Imidazole SCHEMBL10675695 | 0.79 | HCAR2 (0.63) | HCAR2ALDH1A1APPGAAHCAR3 | |
| Pyrrole SCHEMBL5264307 | 0.79 | HCAR2 (0.42) | HCAR2MEN1KMT2ABCAT2TBXA2R | |
| Niacin SCHEMBL5485587 | 0.79 | ALDH1A1 (0.78) | HCAR2ALDH1A1APPGAAHCAR3 | |
| Methylamine SCHEMBL27659538 | 0.78 | HCAR2 (0.85) | HCAR2ALDH1A1APPGAAHCAR3 | |
| Urea SCHEMBL28229729 | 0.78 | HCAR2 (0.85) | HCAR2ALDH1A1APPGAAHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070299091-A1 | Azaindole Carboxamides | GMEINER PETER | 2007-12-27 | — | — | US | disclosed |
| CN-101056878-A | Azaindole carboxamides | SCHVARZ PHARMA AG (DE) | 2007-10-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299091-A1 | Azaindole Carboxamides | TPH1, TPH2, HTR1A | HCAR2 443/4885ALDH1A1 505/4885APP 3220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.