Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL29170928 | 0.91 | NAAA (0.42) | ALDH1A1CES2CES1CA12CA9 | |
| Toluene SCHEMBL11498470 | 0.90 | CA12 (0.42) | LMNATSHRACHEALOX12ALDH1A1 | |
| Toluene SCHEMBL28083276 | 0.89 | CA12 (0.41) | LMNATSHRACHEALOX12ALDH1A1 | |
| Toluene SCHEMBL27457082 | 0.88 | TSHR (0.42) | LMNATSHRACHEALOX12ALDH1A1 | |
| Toluene SCHEMBL3695876 | 0.85 | KMT2A (0.47) | LMNATSHRACHEALOX12ALDH1A1 | |
| Toluene SCHEMBL28496701 | 0.83 | ALDH1A1 (0.42) | LMNATSHRACHEALOX12ALDH1A1 | |
| Toluene SCHEMBL28166100 | 0.83 | LMNA (0.46) | LMNATSHRACHEALOX12ALDH1A1 | |
| Toluene SCHEMBL27810041 | 0.82 | LMNA (0.55) | LMNATSHRACHEALOX12ALDH1A1 | |
| Toluene SCHEMBL28888307 | 0.82 | ALDH1A1 (0.43) | LMNAALDH1A1CYP3A4CYP2C9CYP2C19 | |
| Toluene SCHEMBL27824434 | 0.80 | LMNA (0.52) | LMNATSHRACHEALOX12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120029223-A1 | METHOD FOR PRODUCTION OF SUBSTITUTED ALKYL MALONIC ESTERS AND DERIVATIVES THEREOF | APOSENSE LTD. (IL) | 2012-02-02 | — | — | US | disclosed |
| WO-2012014195-A1 | METHOD FOR PRODUCTION OF SUBSTITUTED ALKYL MALONIC ESTERS AND DERIVATIVES THEREOF | APOSENSE LTD. (IL) | 2012-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120029223-A1 | METHOD FOR PRODUCTION OF SUBSTITUTED ALKYL MALONIC ESTERS AND DERIVATIVES THEREOF | ME1, MAL2, ME3 | LMNA 3402/4885TSHR 3057/4885ACHE 2157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.