Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | IGF1R | P08069 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5272692 | 0.85 | SIRT1 (0.54) | RAB9ANPC1ALDH1A1SMN1; SMN2SIRT1 | |
| SCHEMBL5266990 | 0.82 | CFTR (0.60) | RAB9ANPC1MEN1KMT2A | |
| SCHEMBL5268958 | 0.82 | RAB9A (0.52) | RAB9ANPC1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL5266006 | 0.79 | RAB9A (0.51) | RAB9ANPC1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL5265736 | 0.78 | RAB9A (0.49) | RAB9ANPC1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL4281575 | 0.78 | RAB9A (0.48) | RAB9ANPC1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL5265256 | 0.78 | RAB9A (0.57) | RAB9ANPC1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL13816928 | 0.77 | RAB9A (0.54) | RAB9ANPC1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4292338 | 0.77 | SIRT1 (0.60) | RAB9ANPC1SMN1; SMN2POLBSIRT1 | |
| SCHEMBL5266786 | 0.77 | MEN1 (0.54) | RAB9ANPC1ALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |