Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 2/20 | 0.49 |
| ▸ | CCKBR | P32239 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5265901 | 0.84 | SLC40A1 (0.53) | SLC40A1RELAALDH1A1MAPTKCNMA1 | |
| SCHEMBL5268091 | 0.82 | LMNA (0.55) | POLBALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL5274156 | 0.82 | SLC40A1 (0.48) | SLC40A1RELAALDH1A1MAPTKCNMA1 | |
| SCHEMBL5271535 | 0.78 | SLC40A1 (0.49) | SLC40A1RELAPOLBMAPTLMNA | |
| SCHEMBL5269033 | 0.77 | RAB9A (0.49) | SLC40A1RELAPOLBMAPTLMNA | |
| SCHEMBL5268978 | 0.75 | POLB (0.53) | SLC40A1RELAPOLBALDH1A1KMT2A | |
| SCHEMBL5267751 | 0.74 | NPC1 (0.56) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL5273212 | 0.73 | ALDH1A1 (0.47) | POLBALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL5265851 | 0.73 | MCL1 (0.48) | CCKBRALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL5271765 | 0.72 | ALDH1A1 (0.48) | CCKBRALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |