Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.58 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | CCKBR | P32239 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5268751 | 0.86 | LMNA (0.53) | POLBALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL5268206 | 0.82 | HPGD (0.53) | POLBALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL5268260 | 0.81 | MAPT (0.51) | POLBALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL5272692 | 0.81 | SIRT1 (0.54) | ALDH1A1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL2930131 | 0.81 | MAPT (0.55) | POLBALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL5272614 | 0.80 | CYP1A2 (0.53) | POLBALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL5267455 | 0.79 | SMN1; SMN2 (0.63) | POLBALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL5269122 | 0.79 | ALDH1A1 (0.54) | POLBCTDSP1ALDH1A1MAPTKMT2A | |
| SCHEMBL5265275 | 0.79 | ALDH1A1 (0.54) | POLBALDH1A1MAPTLMNATP53 | |
| SCHEMBL5266740 | 0.78 | TDP1 (0.49) | POLBALDH1A1MAPTLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |