Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MLYCD | O95822 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5267166 | 0.87 | NPC1 (0.52) | LMNANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL4288644 | 0.85 | ALDH1A1 (0.59) | LMNANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL5270571 | 0.84 | KMT2A (0.59) | NPC1RAB9AMEN1ALDH1A1KMT2A | |
| SCHEMBL5269280 | 0.84 | CYP1A2 (0.58) | LMNANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL5266469 | 0.82 | SMN1; SMN2 (0.56) | LMNANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL5269233 | 0.81 | KMT2A (0.51) | LMNANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL5272569 | 0.81 | MAPT (0.58) | LMNANPC1RAB9AMEN1KMT2A | |
| SCHEMBL5267186 | 0.80 | NAPRT (0.51) | NPC1RAB9AMEN1ALDH1A1KMT2A | |
| SCHEMBL5265834 | 0.80 | SIRT1 (0.53) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5267455 | 0.79 | SMN1; SMN2 (0.63) | LMNAMEN1ALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |