Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | FTO | Q9C0B1 | 5/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.64 |
| ▸ | RECQL | P46063 | 2/20 | 0.64 |
| ▸ | BLM | P54132 | 2/20 | 0.64 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.64 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | GNG2 | P59768 | 1/20 | 0.60 |
| ▸ | GNB1 | P62873 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29376609 | 1.00 | MAPT (0.64) | MAPTMEN1KMT2AFTOTDP1 | |
| SCHEMBL5270629 | 0.93 | FTO (0.73) | MAPTMEN1KMT2AFTOTDP1 | |
| SCHEMBL31110329 | 0.93 | FTO (0.65) | MAPTMEN1KMT2AFTOTDP1 | |
| SCHEMBL29362878 | 0.93 | FTO (0.73) | MAPTMEN1KMT2AFTOTDP1 | |
| SCHEMBL16281970 | 0.91 | MAPT (0.65) | MAPTMEN1KMT2AFTOTDP1 | |
| SCHEMBL29583321 | 0.88 | FTO (0.62) | MAPTMEN1KMT2AFTOTDP1 | |
| SCHEMBL21708060 | 0.88 | FTO (0.62) | MAPTMEN1KMT2AFTOTDP1 | |
| SCHEMBL5266530 | 0.86 | FTO (0.57) | MAPTMEN1KMT2AFTOTDP1 | |
| SCHEMBL29365877 | 0.86 | FTO (0.57) | MAPTMEN1KMT2AFTOTDP1 | |
| SCHEMBL5271242 | 0.86 | FTO (0.60) | MAPTMEN1KMT2AFTOTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110275558-A1 | LANTHIONINE SYNTHETASE COMPONENT C-LIKE PROTEINS AS MOLECULAR TARGETS FOR PREVENTING AND TREATING DISEASES AND DISORDERS | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2011-11-10 | — | — | US | claimed |
| WO-2023004400-A1 | DIBENZOXANTHENE QUENCHERS, USES, AND METHODS OF PREPARATION | Life Technologies Corporation (US) | 2023-01-26 | — | — | WO | disclosed |
| US-20210087238-A1 | CELL PENETRATING PEPTIDES AND RELATED COMPOSITIONS AND METHODS | PYC Therapeutics Limited (AU) | 2021-03-25 | — | — | US | disclosed |
| EP-2813892-B1 | Photoresist underlayer film-forming composition and pattern forming processes | SHINETSU CHEMICAL CO (JP) | 2020-06-17 | — | — | EP | disclosed |
| EP-2567225-B1 | LANTHIONINE SYNTHETASE COMPONENT C-LIKE PROTEINS AS MOLECULAR TARGETS FOR PREVENTING AND TREATING DISEASES AND DISORDERS | VIRGINIA TECH INTELLECTUAL PROPERTIES INC (US) | 2019-10-02 | — | — | EP | disclosed |
| US-20180057516-A1 | REAGENTS USEFUL FOR SYNTHESIZING RHODAMINE-LABELED OLIGONUCLEOTIDES | APPLIED BIOSYSTEMS, LLC (US) | 2018-03-01 | — | — | US | disclosed |
| US-9783560-B2 | Reagents useful for synthesizing rhodamine-labeled oligonucleotides | APPLIED BIOSYSTEMS, LLC (US) | 2017-10-10 | — | — | US | disclosed |
| US-20160223558-A1 | ANALYTE DETECTION USING NEAR-INFRARED FLUOROPHORES | PORTLAND STATE UNIVERSITY (US) | 2016-08-04 | — | — | US | disclosed |
| US-9250246-B2 | Near-infrared fluorescent dyes with large stokes shifts | PORTLAND STATE UNIVERSITY (US) | 2016-02-02 | — | — | US | disclosed |
| US-9136121-B2 | Underlayer film-forming composition and pattern forming process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2015-09-15 | — | — | US | disclosed |
| US-20110275558-A1 | LANTHIONINE SYNTHETASE COMPONENT C-LIKE PROTEINS AS MOLECULAR TARGETS FOR PREVENTING AND TREATING DISEASES AND DISORDERS | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2011-11-10 | — | — | US | disclosed |
| US-20110275558-A1 | LANTHIONINE SYNTHETASE COMPONENT C-LIKE PROTEINS AS MOLECULAR TARGETS FOR PREVENTING AND TREATING DISEASES AND DISORDERS | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2011-11-10 | — | — | US | disclosed |
| US-20110275558-A1 | LANTHIONINE SYNTHETASE COMPONENT C-LIKE PROTEINS AS MOLECULAR TARGETS FOR PREVENTING AND TREATING DISEASES AND DISORDERS | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2011-11-10 | — | — | US | disclosed |
| US-20100051826-A1 | Fluorescent Xanthenes and White Light Fluorophores | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE | 2010-03-04 | — | — | US | disclosed |
| US-20090253118-A1 | LUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES | VERSITECH LIMITED (CN) | 2009-10-08 | — | — | US | disclosed |
| US-20090253118-A1 | LUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES | VERSITECH LIMITED (CN) | 2009-10-08 | — | — | US | disclosed |
| WO-2009121247-A1 | LUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES | VERSITECH LIMITED (CN) | 2009-10-08 | — | — | WO | disclosed |
| US-20080071070-A1 | Coupling with phosphoramidite reagent; solid phase synthesis | APPLERA CORPORATION (US) | 2008-03-20 | — | — | US | disclosed |
| WO-2007115265-A9 | REAGENTS USEFUL FOR SYNTHESIZING RHODAMINE-LABELED OLIGONUCLEOTIDES | APPLERA CORP (US) | 2007-11-29 | — | — | WO | disclosed |
| WO-2007115265-A2 | REAGENTS USEFUL FOR SYNTHESIZING RHODAMINE-LABELED OLIGONUCLEOTIDES | APPLIED BIOSYSTEMS INC. (US) | 2007-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253118-A1 | LUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES | ROS1, LPO, HMOX1 | MAPT 4349/4885MEN1 4478/4885KMT2A 3345/4885 |
| US-20100051826-A1 | Fluorescent Xanthenes and White Light Fluorophores | XPOT, XPO6, XPO7 | MAPT 343/4885MEN1 1318/4885KMT2A 4450/4885 |
| US-20160223558-A1 | ANALYTE DETECTION USING NEAR-INFRARED FLUOROPHORES | BLVRB, CBR3, AKR7A2 | MAPT 4472/4885MEN1 3653/4885KMT2A 2373/4885 |
| US-20080071070-A1 | Coupling with phosphoramidite reagent; solid phase synthesis | RTCB, RNGTT, PHAX | MAPT 2656/4885MEN1 2877/4885KMT2A 2455/4885 |
| US-20210087238-A1 | CELL PENETRATING PEPTIDES AND RELATED COMPOSITIONS AND METHODS | VIP, IAPP, LNPEP | MAPT 2566/4885MEN1 2738/4885KMT2A 4816/4885 |
| US-20110275558-A1 | LANTHIONINE SYNTHETASE COMPONENT C-LIKE PROTEINS AS MOLECULAR TARGETS FOR PREVENTING AND TREATING DISEASES AND DISORDERS | LANCL2, ACSL1, LANCL1 | MAPT 4166/4885MEN1 4389/4885KMT2A 4112/4885 |
| US-20180057516-A1 | REAGENTS USEFUL FOR SYNTHESIZING RHODAMINE-LABELED OLIGONUCLEOTIDES | RTCB, RRM2B, SNRPE | MAPT 3503/4885MEN1 3967/4885KMT2A 3778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.