Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 18/20 | 0.55 |
| ▸ | DRD2 | P14416 | 15/20 | 0.55 |
| ▸ | HTR1A | P08908 | 7/20 | 0.55 |
| ▸ | HTR2A | P28223 | 6/20 | 0.55 |
| ▸ | HTR2C | P28335 | 6/20 | 0.55 |
| ▸ | DRD4 | P21917 | 8/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5261982 | 0.95 | DRD2 (0.53) | DRD3DRD2HTR1AHTR2AHTR2C | |
| SCHEMBL5265394 | 0.94 | DRD2 (0.53) | DRD3DRD2HTR1AHTR2AHTR2C | |
| SCHEMBL5265021 | 0.85 | HTR1A (0.48) | DRD3DRD2HTR1AHTR2AHTR2C | |
| SCHEMBL14339848 | 0.82 | DRD3 (0.76) | DRD3DRD2HTR1AHTR2AHTR2C | |
| SCHEMBL14339857 | 0.82 | DRD2 (0.53) | DRD3DRD2HTR1AHTR2AHTR2C | |
| SCHEMBL5468095 | 0.81 | HTR1A (0.43) | DRD3DRD2HTR1AHTR2AHTR2C | |
| SCHEMBL5266898 | 0.81 | DRD2 (0.49) | DRD3DRD2HTR1AHTR2AHTR2C | |
| SCHEMBL5263145 | 0.80 | DRD2 (0.49) | DRD3DRD2HTR1AHTR2AHTR2C | |
| SCHEMBL5264074 | 0.80 | DRD2 (0.78) | DRD3DRD2HTR1AHTR2AHTR2C | |
| SCHEMBL5262499 | 0.78 | DRD3 (0.44) | DRD3DRD2HTR1AHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070299091-A1 | Azaindole Carboxamides | GMEINER PETER | 2007-12-27 | — | — | US | disclosed |
| US-20070299091-A1 | Azaindole Carboxamides | GMEINER PETER | 2007-12-27 | — | — | US | disclosed |
| EP-1771448-A1 | AZAINDOLE CARBOXAMIDES | SCHWARZ PHARMA AG (DE) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006050976-A1 | AZAINDOLE CARBOXAMIDES | SCHWARZ PHARMA AG (DE) | 2006-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299091-A1 | Azaindole Carboxamides | TPH1, TPH2, HTR1A | DRD3 176/4885DRD2 64/4885HTR1A 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.