Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.78 |
| ▸ | DRD3 | P35462 | 10/20 | 0.78 |
| ▸ | DRD4 | P21917 | 9/20 | 0.78 |
| ▸ | HTR1A | P08908 | 3/20 | 0.65 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.65 |
| ▸ | DRD1 | P21728 | 2/20 | 0.65 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.65 |
| ▸ | HTR2A | P28223 | 2/20 | 0.65 |
| ▸ | HTR2C | P28335 | 2/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.65 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.65 |
| ▸ | HTR2B | P41595 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5504452 | 0.88 | DRD3 (1.00) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL6357580 | 0.85 | DRD3 (0.94) | DRD2DRD3DRD4HTR1AADRA2A | |
| SCHEMBL5264300 | 0.84 | DRD2 (0.66) | DRD2DRD3DRD4HTR1AADRA1D | |
| SCHEMBL14339848 | 0.83 | DRD3 (0.76) | DRD2DRD3DRD4HTR1ADRD1 | |
| Hydrochloric Acid SCHEMBL9134513 | 0.83 | DRD3 (0.91) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL9653912 | 0.81 | DRD2 (0.74) | DRD2DRD3DRD4HTR1AADRA1D | |
| SCHEMBL9650872 | 0.80 | DRD2 (0.80) | DRD2DRD3DRD4HTR1AADRA1D | |
| SCHEMBL5266646 | 0.80 | DRD3 (0.55) | DRD2DRD3DRD4HTR1AHTR2A | |
| Bp-897 SCHEMBL26086545 | 0.79 | DRD2 (0.96) | DRD2DRD3DRD4HTR1AADRA2A | |
| Bp-897 SCHEMBL30027453 | 0.79 | DRD2 (1.00) | DRD2DRD3DRD4HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070299091-A1 | Azaindole Carboxamides | GMEINER PETER | 2007-12-27 | — | — | US | disclosed |
| US-20070299091-A1 | Azaindole Carboxamides | GMEINER PETER | 2007-12-27 | — | — | US | disclosed |
| EP-1771448-A1 | AZAINDOLE CARBOXAMIDES | SCHWARZ PHARMA AG (DE) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006050976-A1 | AZAINDOLE CARBOXAMIDES | SCHWARZ PHARMA AG (DE) | 2006-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299091-A1 | Azaindole Carboxamides | TPH1, TPH2, HTR1A | DRD2 64/4885DRD3 176/4885DRD4 94/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.