Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5270615 | 0.87 | PLK1 (0.58) | F10GAATP53NPC1RAB9A | |
| SCHEMBL5271746 | 0.86 | ALDH1A1 (0.50) | F10TP53NPC1RAB9AKMT2A | |
| SCHEMBL5273573 | 0.85 | TRPV1 (0.49) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5267481 | 0.85 | MDM4 (0.49) | GAATP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5273753 | 0.84 | MLYCD (0.49) | GPR35KMT2AHDAC4KDM4EMAPT | |
| SCHEMBL5266131 | 0.84 | LMNA (0.50) | GAANPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL5272675 | 0.82 | RAB9A (0.60) | F10GAATP53NPC1RAB9A | |
| SCHEMBL5266584 | 0.82 | RAB9A (0.54) | F10NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL5265957 | 0.81 | HPGD (0.56) | F10GAARAB9ASMN1; SMN2ALOX15 | |
| SCHEMBL5269927 | 0.79 | LMNA (0.49) | GAATP53SMN1; SMN2ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |