SCHEMBL5266922

SCHEMBL5266922

CC1C(=O)N(C)C(=O)N(C)C1=S

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.35
ALDH1A1 P00352 3/20 0.35
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
BLM P54132 1/20 0.32
HSD17B10 Q99714 3/20 0.32
KDM4A O75164 1/20 0.32
KDM4C Q9H3R0 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ADRA2C P18825 1/20 0.31
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
THRB P10828 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL200674 0.82 MAPT (0.41) MAPTALDH1A1MEN1KMT2ABLM
SCHEMBL1263355 0.79 MAPT (0.40) MAPTALDH1A1MEN1KMT2ABLM
Calcium SCHEMBL30891545 0.79 MAPT (0.40) MAPTALDH1A1MEN1KMT2ABLM
SCHEMBL1263023 0.79 MAPT (0.40) MAPTALDH1A1MEN1KMT2ABLM
SCHEMBL4006398 0.79 MAPT (0.40) MAPTALDH1A1MEN1KMT2ABLM
SCHEMBL3267916 0.72 MEN1 (0.35) MEN1KMT2ABLM
SCHEMBL9337272 0.71 ALDH1A1 (0.40) MAPTALDH1A1MEN1KMT2AHSD17B10
SCHEMBL10311254 0.70
SCHEMBL12806567 0.68 ADRA2C (0.38) MEN1KMT2AADRA2C
SCHEMBL16866980 0.67 MEN1 (0.32) MAPTALDH1A1MEN1KMT2ABLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1459726-B1 ADHESIVES FOR DENTAL USE TOKUYAMA CORP (JP) 2013-10-02 EP disclosed
EP-1431315-B1 Photopolymerization initiator and photopolymerizable composition TOKUYAMA CORP (JP) 2007-10-17 EP disclosed
US-7041714-B2 Dental adhesive TOKUYAMA CORPORATION (JP) 2006-05-09 US disclosed
US-20040186195-A1 Photopolymerization initiator and photopolymerizable composition TOKUYAMA CORPORATION (JP) 2004-09-23 US disclosed
EP-1459726-A1 ADHESIVES FOR DENTAL USE TOKUYAMA CORPORATION (JP) 2004-09-22 EP disclosed
EP-1431315-A2 Photopolymerization initiator and photopolymerizable composition Tokuyama Corporation (JP) 2004-06-23 EP disclosed
US-20040077746-A1 Adhesives for dental use TOKUYAMA CORPORATION (JP) 2004-04-22 US disclosed
US-5290172-A Method for preparing a tooth surface for bonding GC CORPORATION (JP) 1994-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040077746-A1 Adhesives for dental use ICAM1, CDH1, VCAM1 MAPT 749/4885ALDH1A1 242/4885MEN1 4143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.