Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5271209 | 0.89 | — | — | |
| SCHEMBL5273430 | 0.78 | PGR (0.37) | NOTUM | |
| SCHEMBL5271201 | 0.78 | PGR (0.37) | NOTUMAKR1B1 | |
| SCHEMBL1400074 | 0.76 | NOTUM (0.36) | NOTUMAKR1B1 | |
| SCHEMBL5269873 | 0.75 | ALDH1A1 (0.37) | — | |
| SCHEMBL5269692 | 0.72 | NR3C1 (0.37) | — | |
| SCHEMBL5559796 | 0.72 | NOTUM (0.31) | NOTUMAKR1B1 | |
| SCHEMBL5270297 | 0.71 | OPRD1 (0.35) | — | |
| SCHEMBL2317446 | 0.70 | NOTUM (0.37) | NOTUMAKR1B1 | |
| SCHEMBL2317447 | 0.70 | NOTUM (0.37) | NOTUMAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1600446-B1 | New 3,3-dimethyl-5-cyano-benzoxepine derivatives useful for the preparation of 5-formyl-benzoxepine derivatives | MERCK SANTE SAS (FR) | 2007-10-17 | — | — | EP | claimed |
| EP-1600446-A1 | New 3,3-dimethyl-5-cyano-benzoxepine derivatives useful for the preparation of 5-formyl-benzoxepine derivatives | Merck Sante (FR) | 2005-11-30 | — | — | EP | claimed |
| WO-2005111012-A1 | NEW 3,3-DIMETHYL-5-CYANO-BENZOXEPINES DERIVATIVES USEFUL FOR THE PREPARATION OF 5-FORMYL-BENZOXEPINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2005-11-24 | — | — | WO | claimed |
| EP-1600446-B1 | New 3,3-dimethyl-5-cyano-benzoxepine derivatives useful for the preparation of 5-formyl-benzoxepine derivatives | MERCK SANTE SAS (FR) | 2007-10-17 | — | — | EP | disclosed |
| EP-1600446-A1 | New 3,3-dimethyl-5-cyano-benzoxepine derivatives useful for the preparation of 5-formyl-benzoxepine derivatives | Merck Sante (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2005111012-A1 | NEW 3,3-DIMETHYL-5-CYANO-BENZOXEPINES DERIVATIVES USEFUL FOR THE PREPARATION OF 5-FORMYL-BENZOXEPINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2005-11-24 | — | — | WO | disclosed |