Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 5/20 | 0.37 |
| ▸ | MAOA | P21397 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27323515 | 0.72 | CCR2 (0.46) | KDM4EMAPTTDP1GAAPKM | |
| SCHEMBL2123643 | 0.71 | KDM4E (0.48) | IDH1KDM4EMAPTTDP1GAA | |
| SCHEMBL396279 | 0.66 | HTR6 (0.66) | NPC1BRD4 | |
| SCHEMBL5134071 | 0.66 | HTR6 (0.66) | NPC1BRD4 | |
| Diphenylmethane SCHEMBL17414841 | 0.64 | MAOB (0.64) | IDH1KDM4EMAPTTDP1GAA | |
| SCHEMBL8771463 | 0.64 | CYP3A4 (0.78) | MAPTTDP1GAAALDH1A1CYP3A4 | |
| 4,4'-Methylenedianiline SCHEMBL28946261 | 0.64 | CYP3A4 (0.78) | MAPTTDP1GAAALDH1A1CYP3A4 | |
| SCHEMBL202238 | 0.64 | CYP3A4 (0.78) | MAPTTDP1GAAALDH1A1CYP3A4 | |
| SCHEMBL1122491 | 0.64 | NOS1 (0.52) | KDM4EMAPTALDH1A1MAOBMAOA | |
| SCHEMBL16355908 | 0.64 | ALOX5 (0.44) | IDH1GAAPKMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781379-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | The Procter and Gamble Company (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006026495-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2006-03-09 | — | — | WO | disclosed |