Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5267582 | 0.84 | LMNA (0.56) | ALDH1A1RAB9ASMN1; SMN2HSD17B10KMT2A | |
| SCHEMBL5265290 | 0.83 | KDM4E (0.46) | CYP1A2CYP2C9CYP2C19KDM4EPOLB | |
| SCHEMBL5269503 | 0.82 | RAB9A (0.61) | KDM4EPOLBALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL5267186 | 0.81 | NAPRT (0.51) | KDM4EPOLBALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL5270659 | 0.81 | KDM4E (0.44) | CYP1A2CYP2C9CYP2C19KDM4EPOLB | |
| SCHEMBL5272569 | 0.80 | MAPT (0.58) | KDM4EPOLBRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL13816814 | 0.80 | FLT3 (0.49) | POLBALDH1A1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL3667956 | 0.79 | KMT2A (0.69) | CYP1A2CYP2C9CYP2C19KDM4EPOLB | |
| SCHEMBL5265834 | 0.79 | SIRT1 (0.53) | KDM4EPOLBRAB9AKMT2AMEN1 | |
| SCHEMBL5271885 | 0.78 | MAPT (0.55) | KDM4EALDH1A1SMN1; SMN2HSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |