Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5266914 | 0.87 | MAPT (0.41) | MAPTMEN1POLBKMT2APTPN5 | |
| SCHEMBL5269766 | 0.83 | TOP2A (0.38) | SCN8ASCN10APTPN5PPARDFFAR1 | |
| SCHEMBL5573980 | 0.80 | MAPT (0.40) | MAPTMEN1POLBKMT2APPARD | |
| SCHEMBL5271428 | 0.79 | MAPT (0.41) | MAPTMEN1POLBKMT2APTPN5 | |
| SCHEMBL5268298 | 0.76 | MAPT (0.41) | MAPTMEN1POLBKMT2ACYP2C9 | |
| SCHEMBL5509080 | 0.76 | PTPN5 (0.37) | MAPTSCN8ASCN10APTPN5PPARD | |
| SCHEMBL5267628 | 0.75 | PPARD (0.39) | MAPTMEN1POLBKMT2APPARD | |
| SCHEMBL5270824 | 0.75 | PTPN1 (0.37) | MAPTMEN1POLBKMT2APTPN5 | |
| SCHEMBL5339470 | 0.74 | GPR35 (0.37) | MAPTKMT2ASCN8ASCN10APTPN5 | |
| SCHEMBL5339900 | 0.74 | BRD4 (0.40) | MEN1POLBKMT2ABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1838669-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006077365-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |