Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | FLT3 | P36888 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29518984 | 1.00 | CA12 (0.48) | CA12CA1CA2LMNACA3 | |
| SCHEMBL29940757 | 0.83 | KDM4E (0.48) | CA12CA1CA2LMNACA3 | |
| SCHEMBL28906146 | 0.83 | KDM4E (0.48) | CA12CA1CA2LMNACA3 | |
| SCHEMBL2441217 | 0.76 | FAAH (0.45) | CA12CA1CA2LMNACA3 | |
| SCHEMBL8103815 | 0.73 | CA12 (0.46) | CA12CA1CA2LMNACA3 | |
| SCHEMBL4930668 | 0.73 | CA12 (0.46) | CA12CA1CA2LMNACA3 | |
| SCHEMBL8358457 | 0.73 | NPC1 (0.45) | CA2IDO1ESR1ESR2KDM4E | |
| SCHEMBL15922141 | 0.73 | F9 (0.43) | CA12CA1CA9IDO1ESR1 | |
| SCHEMBL210393 | 0.71 | HIF1A (0.47) | CA12CA1CA2LMNACA3 | |
| SCHEMBL468359 | 0.71 | ESR1 (0.53) | CA12CA1CA2LMNACA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 590 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2903978-B1 | GDF-8 INHIBITORS | RIGEL PHARMACEUTICALS INC (US) | 2022-12-07 | — | — | EP | claimed |
| US-11427591-B2 | Kinase inhibitors | INSILICO MEDICINE IP LIMITED (HK) | 2022-08-30 | — | — | US | claimed |
| US-20200035418-A1 | PASSIVATION OF DEFECTS IN PEROVSKITE MATERIALS FOR IMPROVED SOLAR CELL EFFICIENCY AND STABILITY | NUTECH VENTURES | 2020-01-30 | — | — | US | claimed |
| WO-2018152494-A1 | PASSIVATION OF DEFECTS IN PEROVSKITE MATERIALS FOR IMPROVED SOLAR CELL EFFICIENCY AND STABILITY | NUTECH VENTURES (US) | 2018-08-23 | — | — | WO | claimed |
| US-7977360-B2 | Benzo[d]isoxazol-3-yl-amine compounds and their use as vanilloid receptor ligands | GRUENENTHAL GMBH (DE) | 2011-07-12 | — | — | US | claimed |
| EP-1881967-B1 | SUBSTITUTED BENZO(D)ISOXAZOL-3-YL AMINE COMPOUNDS AS ANALGESICS | GRUENENTHAL GMBH (DE) | 2010-04-28 | — | — | EP | claimed |
| US-7696238-B2 | Substituted benzo[d]isoxazol-3-yl amine compounds as analgesics | GRUENENTHAL GMBH (DE) | 2010-04-13 | — | — | US | claimed |
| EP-1451163-B1 | 3-AMIDO-1,2-BENZOISOXAZOLE DERIVATIVES, PROCESS FOR PREPARATION, AND USE THEREOF | DONG WHA PHARM CO LTD (KR) | 2010-02-17 | — | — | EP | claimed |
| EP-1888541-B1 | BENZO(D)ISOXAZOL-3-YL-AMINE COMPOUNDS AND THEIR USE AS VANILLOID RECEPTOR LIGANDS | GRUENENTHAL GMBH (DE) | 2009-08-05 | — | — | EP | claimed |
| US-20090042945-A1 | Benzo[d]isoxazol-3-yl-amine Compounds and Their Use as Vanilloid Receptor Ligands | GRUENENTHAL GMBH (DE) | 2009-02-12 | — | — | US | claimed |
| US-7291638-B2 | 3-amido-1,2-benzoisoxazole derivatives, process for preparation, and use thereof | DONGWHA PHARM. IND. CO., LTD. (KR) | 2007-11-06 | — | — | US | claimed |
| US-20050020650-A1 | 3-amido-1,2-benzoisoxazole derivatives, process for preparation, and use thereof | DONG WHA PHARM. CO., LTD. (KR) | 2005-01-27 | — | — | US | claimed |
| EP-1135023-A4 | AMINOBENZISOXAZOLE COMPOUNDS AND LIBRARIES THEREOF | LILLY CO ELI (US) | 2003-03-05 | — | — | EP | claimed |
| EP-1135023-A1 | AMINOBENZISOXAZOLE COMPOUNDS AND LIBRARIES THEREOF | ELI LILLY AND COMPANY (US) | 2001-09-26 | — | — | EP | claimed |
| US-6150390-A | ACCELERATES BONE FORMATION; OSTEOPOROSIS; (LTB-4(LEUKOTRIENE-B-4; 5,12-DIHYDROXYEICOSATETRA-6,8,10,14-ENOIC ACID) RECEPTOR ANTAGONIST | DONG WHA PHARM. IND. CO., LTD. (KR) | 2000-11-21 | — | — | US | claimed |
| EP-0726268-B1 | Substituted benzisoxazole and benzisothiazole herbicidal agents | AMERICAN CYANAMID CO (US) | 2000-11-02 | — | — | EP | claimed |
| EP-1019384-A1 | 3-AMINO-1,2-BENZOISOXAZOLE DERIVATIVES, PROCESS FOR PREPARATION, AND USE THEREOF | DONG WHA PHARMACEUTICAL INDUSTRIAL CO. LTD. (KR) | 2000-07-19 | — | — | EP | claimed |
| WO-2000027199-A1 | AMINOBENZISOXAZOLE COMPOUNDS AND LIBRARIES THEREOF | ELI LILLY AND COMPANY (US) | 2000-05-18 | — | — | WO | claimed |
| WO-1998033779-A1 | 3-AMINO-1,2-BENZOISOXAZOLE DERIVATIVES, PROCESS FOR PREPARATION, AND USE THEREOF | DONG WHA PHARM. IND. CO., LTD. (KR) | 1998-08-06 | — | — | WO | claimed |
| US-4242495-A | COATINGS, MOLDINGS, FOAMS | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1980-12-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11427591-B2 | Kinase inhibitors | DDR1, DDR2, DDRGK1 | CA12 4862/4885CA1 4500/4885CA2 4126/4885 |
| US-20090042945-A1 | Benzo[d]isoxazol-3-yl-amine Compounds and Their Use as Vanilloid Receptor Ligands | TRPV1, TRPV3, TRPV5 | CA12 2549/4885CA1 3307/4885CA2 753/4885 |
| US-20050020650-A1 | 3-amido-1,2-benzoisoxazole derivatives, process for preparation, and use thereof | LTB4R, FPR1, LTB4R2 | CA12 4490/4885CA1 3570/4885CA2 1536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.