Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.41 |
| ▸ | MAP2 | P11137 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4022950 | 0.80 | ALDH1A1 (0.51) | PTGESKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5212831 | 0.76 | ACACB (0.44) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL5215846 | 0.76 | JAK2 (0.39) | PTGESKDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL333804 | 0.76 | PTGES (0.42) | PTGESMEN1KMT2AJAK2RXRA | |
| Hydrochloric Acid SCHEMBL3007569 | 0.76 | PTGES (0.43) | PTGESKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5281847 | 0.75 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL5210645 | 0.74 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL3007123 | 0.74 | PTGES (0.41) | PTGESMEN1KMT2AJAK2MCL1 | |
| Hydrochloric Acid SCHEMBL3016503 | 0.74 | PTGES (0.41) | PTGESMEN1KMT2AJAK2RXRA | |
| SCHEMBL5204577 | 0.74 | PTGES (0.39) | PTGESGPR35PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778632-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-05-02 | — | — | EP | disclosed |
| WO-2005123673-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2005-12-29 | — | — | WO | disclosed |