Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.48 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.46 |
| ▸ | ASAH1 | Q13510 | 3/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3200016 | 0.99 | NAAA (0.50) | NAAALTB4R2ASAH1EPHX1ALDH1A1 | |
| SCHEMBL9508710 | 0.82 | ALDH1A1 (0.50) | NAAAEPHX1ALDH1A1HTTNPC1 | |
| SCHEMBL3200012 | 0.80 | NAAA (0.52) | NAAAEPHX1ALDH1A1HTTNPC1 | |
| SCHEMBL4133486 | 0.80 | NAAA (0.49) | NAAAASAH1EPHX1ALDH1A1HTT | |
| SCHEMBL4137357 | 0.79 | NAAA (0.58) | NAAAASAH1EPHX1ALDH1A1HTT | |
| SCHEMBL3210607 | 0.76 | NAAA (0.49) | NAAAEPHX1ALDH1A1HTTNPC1 | |
| SCHEMBL4137692 | 0.76 | EPHX2 (0.52) | NAAAEPHX1ALDH1A1HTTNPC1 | |
| SCHEMBL4611224 | 0.76 | EGFR (0.47) | NAAALTB4R2ALDH1A1NPC1RAB9A | |
| SCHEMBL7469022 | 0.75 | NAMPT (0.43) | NAAAEPHX1ALDH1A1HTTNPC1 | |
| SCHEMBL13772465 | 0.73 | HSD17B10 (0.47) | NAAAEPHX1ALDH1A1HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1742608-A1 | NOVEL BIAROMATIC COMPOUNDS WHICH ACTIVATE PPARϝ-TYPE RECEPTORS, THEIR PROCESS OF PREPARATION AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2007-01-17 | — | — | EP | disclosed |
| WO-2005108352-A1 | NOVEL BIAROMATIC COMPOUNDS WHICH ACTIVATE PPARϜ-TYPE RECEPTORS, THEIR PROCESS OF PREPARATION AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2005-11-17 | — | — | WO | disclosed |