Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 4/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9508710 | 0.79 | ALDH1A1 (0.50) | NAMPTALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL3051887 | 0.76 | TSHR (0.60) | ALDH1A1HPGDNAAAHTTTSHR | |
| SCHEMBL4133486 | 0.76 | NAAA (0.49) | NAMPTALDH1A1NPC1RAB9ANAAA | |
| SCHEMBL5268847 | 0.75 | NAAA (0.48) | ALDH1A1NPC1RAB9AHPGDNAAA | |
| SCHEMBL3200016 | 0.74 | NAAA (0.50) | NAMPTALDH1A1NAAAEPHX1HTT | |
| SCHEMBL4137692 | 0.73 | EPHX2 (0.52) | NAMPTALDH1A1NPC1RAB9ANAAA | |
| SCHEMBL4137357 | 0.73 | NAAA (0.58) | NAMPTALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL3218535 | 0.72 | NPY2R (0.44) | — | |
| SCHEMBL2732795 | 0.71 | DNM1 (0.52) | HPGD | |
| SCHEMBL7469026 | 0.70 | TP53 (0.47) | ALDH1A1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650476-B1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMA CO LTD (JP) | 2002-06-26 | — | — | EP | disclosed |
| US-6136826-A | AMINOPIPERIDINE COMPOUNDS SUBSTITUTED WITH ALKANOYL | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| US-5760058-A | Peripheral vasodilating agent containing piperidine derivative as active ingredient | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-02 | — | — | US | disclosed |
| US-5656642-A | Peripheral vasodilating agent containing piperidine derivative as active ingredient | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |