Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5269683 | 0.89 | RAB9A (0.51) | ALDH1A1KDM4EHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL5265233 | 0.87 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL5268485 | 0.86 | KCNA5 (0.51) | ALDH1A1KDM4EHSD17B10GAATP53 | |
| SCHEMBL5267514 | 0.86 | F2 (0.46) | ALDH1A1KDM4EHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL13816854 | 0.84 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDPOLBGAA | |
| SCHEMBL5267465 | 0.84 | AR (0.43) | ALDH1A1POLBSMN1; SMN2GAAPKM | |
| SCHEMBL5270827 | 0.84 | KMT2A (0.58) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL5272580 | 0.83 | ALOX15 (0.49) | ALDH1A1KDM4EPOLBGAAPKM | |
| SCHEMBL5269046 | 0.82 | KCNA5 (0.50) | ALDH1A1KDM4ERECQLGAAMAPT | |
| SCHEMBL5271844 | 0.82 | ALDH1A1 (0.52) | ALDH1A1HPGDHSD17B10SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |