Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5267869 | 0.89 | RAB9A (0.47) | ARMAPTSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL5267514 | 0.85 | F2 (0.46) | TP53MAPTSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL5265937 | 0.84 | CCNE2 (0.45) | ARTP53MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL5268993 | 0.84 | ALDH1A1 (0.54) | TP53MAPTSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL5269803 | 0.83 | HPGD (0.48) | TP53MAPTSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL5268887 | 0.81 | KCNK3 (0.39) | MAPTGAAALDH1A1KCNK3KCNK9 | |
| SCHEMBL5265233 | 0.81 | ALDH1A1 (0.44) | TP53MAPTSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL5268485 | 0.81 | KCNA5 (0.51) | TP53MAPTGAAALDH1A1 | |
| SCHEMBL5266632 | 0.81 | CASP1 (0.42) | TP53MAPTSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL5272580 | 0.80 | ALOX15 (0.49) | TP53MAPTGAAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |