Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5270659 | 0.86 | KDM4E (0.44) | KDM4EPOLBHSD17B10ALDH1A1MAPT | |
| SCHEMBL5269280 | 0.83 | CYP1A2 (0.58) | KDM4EPOLBHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL5271386 | 0.81 | ALDH1A1 (0.46) | KDM4EPOLBHSD17B10ALDH1A1MAPT | |
| SCHEMBL5267166 | 0.79 | NPC1 (0.52) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL5269503 | 0.78 | RAB9A (0.61) | KDM4EPOLBHSD17B10ALDH1A1MAPT | |
| SCHEMBL5269814 | 0.78 | LMNA (0.49) | KDM4EPOLBHSD17B10ALDH1A1MAPT | |
| SCHEMBL5270376 | 0.76 | TSHR (0.50) | KDM4EPOLBHSD17B10ALDH1A1MAPT | |
| SCHEMBL13816862 | 0.76 | YTHDC1 (0.41) | KDM4EPOLBHPGDTSHRSMN1; SMN2 | |
| SCHEMBL5273437 | 0.76 | KDM4E (0.44) | KDM4EPOLBHSD17B10ALDH1A1MAPT | |
| SCHEMBL5268734 | 0.75 | KDM4E (0.51) | KDM4EPOLBALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |