Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDX3X | O00571 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5268996 | 0.87 | BCHE (0.49) | MAPTHPGDTDP1KDM4ELMNA | |
| SCHEMBL5270890 | 0.85 | HIF1A (0.44) | MAPTHPGDALDH1A1CA12CA1 | |
| SCHEMBL5273435 | 0.84 | GAA (0.43) | MAPTHPGDKDM4EMEN1LMNA | |
| SCHEMBL5431944 | 0.84 | MAPT (0.61) | MAPTHPGDTDP1KDM4EMEN1 | |
| SCHEMBL5272106 | 0.84 | KDM4E (0.46) | MAPTHPGDTDP1KDM4EMEN1 | |
| SCHEMBL5268852 | 0.84 | HDAC4 (0.44) | MAPTHPGDKDM4EMEN1GAA | |
| SCHEMBL5269215 | 0.84 | ARG1 (0.41) | MAPTHPGDKDM4EMEN1GAA | |
| SCHEMBL5271508 | 0.84 | MAPT (0.39) | MAPTHPGDTDP1KDM4EMEN1 | |
| SCHEMBL5272425 | 0.83 | MAOA (0.42) | MAPTHPGDKDM4EMEN1KMT2A | |
| SCHEMBL5272017 | 0.83 | MAPT (0.39) | MAPTHPGDKDM4EBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1846361-A2 | 3-AMINO-2-AMINOMETHYLPHENOL DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS | Wella Aktiengesellschaft (DE) | 2007-10-24 | — | — | EP | claimed |
| US-20070022546-A1 | 3-Amino-2-aminomethylphenol derivatives and colorants comprising these compounds | PROCTER & GAMBLE COMPANY, THE | 2007-02-01 | — | — | US | claimed |
| WO-2006086374-A2 | 3-AMINO-2-AMINOMETHYLPHENOL DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2006-08-17 | — | — | WO | claimed |
| EP-1846361-A2 | 3-AMINO-2-AMINOMETHYLPHENOL DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS | Wella Aktiengesellschaft (DE) | 2007-10-24 | — | — | EP | disclosed |
| US-20070022546-A1 | 3-Amino-2-aminomethylphenol derivatives and colorants comprising these compounds | PROCTER & GAMBLE COMPANY, THE | 2007-02-01 | — | — | US | disclosed |
| WO-2006086374-A2 | 3-AMINO-2-AMINOMETHYLPHENOL DERIVATIVES AND COLORANTS COMPRISING THESE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2006-08-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070022546-A1 | 3-Amino-2-aminomethylphenol derivatives and colorants comprising these compounds | KRT18, COL2A1, COL1A1 | DDX3X 4320/4885MAPT 317/4885HPGD 690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.