SCHEMBL5269770

SCHEMBL5269770

CCCCCCCCCCCCCCCCc1ccc[c]c1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.51
BID P55957 3/20 0.47
MCL1 Q07820 3/20 0.47
BCL2L1 Q07817 2/20 0.47
BAK1 Q16611 2/20 0.47
KAT8 Q9H7Z6 2/20 0.47
PPARG P37231 1/20 0.47
PPARA Q07869 1/20 0.47
EP300 Q09472 1/20 0.47
KAT2A Q92830 1/20 0.47
KAT2B Q92831 1/20 0.47
KAT5 Q92993 1/20 0.47
SAE1 Q9UBE0 1/20 0.47
ALOX5 P09917 2/20 0.46
PTGS2 P35354 2/20 0.46
TYR P14679 2/20 0.46
TP53 P04637 2/20 0.46
CYP3A4 P08684 2/20 0.46
MEN1 O00255 1/20 0.46
MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5272184 1.00 LIPG (0.51) LIPGBIDMCL1BCL2L1BAK1
SCHEMBL5271863 1.00 LIPG (0.51) LIPGBIDMCL1BCL2L1BAK1
SCHEMBL5270430 1.00 LIPG (0.51) LIPGBIDMCL1BCL2L1BAK1
SCHEMBL5269202 1.00 LIPG (0.51) LIPGBIDMCL1BCL2L1BAK1
SCHEMBL5271616 1.00 LIPG (0.51) LIPGBIDMCL1BCL2L1BAK1
SCHEMBL9174076 0.98 LIPG (0.49) LIPGBIDMCL1BCL2L1BAK1
SCHEMBL6222948 0.93 TYR (0.43) LIPGBIDMCL1BCL2L1BAK1
SCHEMBL9359703 0.85 GABRA1 (0.37) LIPGBIDMCL1BCL2L1BAK1
SCHEMBL21523367 0.80 LIPG (0.49) LIPGBIDMCL1BCL2L1BAK1
SCHEMBL21523321 0.80 LIPG (0.49) LIPGBIDMCL1BCL2L1BAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1243609-B1 SUCCINIMIDE COMPOUNDS AND USE THEREOF IDEMITSU KOSAN CO (JP) 2007-10-24 EP disclosed
US-6906191-B2 Succinimide compounds and use thereof IDEMITSU KOSAN CO., LTD. (JP) 2005-06-14 US disclosed
US-20030018198-A1 Succinimide compounds and use thereof IDEMITSU KOSAN CO., LTD. (JP) 2003-01-23 US disclosed
EP-1243609-A1 SUCCINIMIDE COMPOUNDS AND USE THEREOF IDEMITSU KOSAN CO., LTD. (JP) 2002-09-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030018198-A1 Succinimide compounds and use thereof SRM, SMS, SGMS2 LIPG 1514/4885BID 1066/4885MCL1 4450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.