Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5339470 | 0.92 | GPR35 (0.37) | PPARDACACBACACASCN8ASCN10A | |
| SCHEMBL5342565 | 0.82 | MAPT (0.45) | ACACBACACAMAPTKDM4EALDH1A1 | |
| SCHEMBL5271483 | 0.81 | RORC (0.36) | ACACBACACAEGLN1MAPTKDM4E | |
| SCHEMBL5269571 | 0.77 | PTGER4 (0.39) | PPARDACACBSCN8ASCN10ACYP2C9 | |
| SCHEMBL5573980 | 0.76 | MAPT (0.40) | PPARDPPARAMAPTKDM4EALDH1A1 | |
| SCHEMBL5269374 | 0.76 | FFAR4 (0.36) | — | |
| SCHEMBL5273163 | 0.75 | PRKAB2 (0.36) | PPARDPPARAEGLN1 | |
| SCHEMBL5274888 | 0.75 | KDM4E (0.49) | MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL5268671 | 0.74 | KDM4E (0.52) | MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL5273364 | 0.74 | KDM4E (0.44) | ACACBACACAMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844013-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006077364-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |