Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | STAT3 | P40763 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2930131 | 0.84 | MAPT (0.55) | MAPTKMT2AMEN1STAT3RAB9A | |
| SCHEMBL5265813 | 0.82 | NPC1 (0.51) | HRH3MAPTKMT2AMEN1RAB9A | |
| SCHEMBL5272614 | 0.81 | CYP1A2 (0.53) | HRH3MAPTPAX8NPSR1USP2 | |
| SCHEMBL5270089 | 0.80 | GAA (0.59) | MAPTKMT2AMEN1HSD17B10LMNA | |
| SCHEMBL5268260 | 0.80 | MAPT (0.51) | HRH3MAPTKMT2AMEN1STAT3 | |
| SCHEMBL5270583 | 0.80 | RAB9A (0.51) | MAPTKMT2AMEN1STAT3RAB9A | |
| SCHEMBL5268751 | 0.79 | LMNA (0.53) | HRH3MAPTKMT2AMEN1STAT3 | |
| SCHEMBL5267757 | 0.78 | KMT2A (0.47) | KMT2AMEN1RAB9ALMNAPKM | |
| SCHEMBL954893 | 0.77 | ALDH1A1 (0.50) | HRH3MAPTKMT2AMEN1STAT3 | |
| SCHEMBL5272564 | 0.76 | NPY4R (0.57) | MAPTNPSR1RAB9ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |