Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5212228 | 1.00 | RECQL (0.38) | RECQLTSHRSMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL5212219 | 1.00 | RECQL (0.38) | RECQLTSHRSMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL5212955 | 0.84 | L3MBTL1 (0.40) | L3MBTL1MAPK1FFAR1MTNR1AALDH1A1 | |
| SCHEMBL5212946 | 0.84 | L3MBTL1 (0.40) | L3MBTL1MAPK1FFAR1MTNR1AALDH1A1 | |
| SCHEMBL5210668 | 0.83 | CA2 (0.40) | FFAR1CA2MTNR1AALDH1A1POLB | |
| SCHEMBL5211766 | 0.79 | HTR6 (0.41) | RECQLSMN1; SMN2L3MBTL1FFAR1CA2 | |
| SCHEMBL5215763 | 0.75 | LMNA (0.39) | RECQLSMN1; SMN2L3MBTL1CA2ALDH1A1 | |
| SCHEMBL5746370 | 0.71 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL2798211 | 0.71 | TAAR1 (0.53) | SMN1; SMN2L3MBTL1 | |
| SCHEMBL6794898 | 0.69 | MTNR1A (0.46) | L3MBTL1MAPK1FFAR1MTNR1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554264-B1 | MEDICINAL ARYLETHANOLAMINE COMPOUNDS | GLAXO GROUP LTD (GB) | 2007-08-08 | — | — | EP | disclosed |