Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6021912 | 0.92 | CHRM2 (0.56) | CHRM2ACHEBCHECHRM4CD274 | |
| SCHEMBL4692594 | 0.90 | CHRM2 (0.42) | CHRM2ACHEBCHEMCHR1 | |
| SCHEMBL4696924 | 0.89 | CHRM2 (0.41) | CHRM2ACHEBCHEMCHR1PDCD1 | |
| SCHEMBL4693819 | 0.88 | CHRM2 (0.42) | CHRM2ACHEBCHEMCHR1 | |
| SCHEMBL4694020 | 0.88 | CHRM2 (0.40) | CHRM2ACHEBCHEMCHR1 | |
| SCHEMBL4694973 | 0.87 | MCHR1 (0.40) | CHRM2ACHEBCHEMCHR1 | |
| SCHEMBL4692420 | 0.85 | MCHR1 (0.38) | CHRM2ACHEBCHEMCHR1 | |
| SCHEMBL6021990 | 0.83 | CHRM2 (0.41) | CHRM2PDCD1CD274 | |
| SCHEMBL4696795 | 0.82 | CHRM2 (0.35) | CHRM2ACHE | |
| SCHEMBL4695275 | 0.82 | CHRM2 (0.35) | CHRM2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856112-A1 | BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | Theravance, Inc. (US) | 2007-11-21 | — | — | EP | claimed |
| WO-2006099032-A1 | BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | THERAVANCE, INC. (US) | 2006-09-21 | — | — | WO | claimed |