SCHEMBL5280180

SCHEMBL5280180

CC(C)CC1(c2ccccc2)N=NN=N1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
HTT P42858 1/20 0.36
ELANE P08246 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ATM Q13315 1/20 0.35
CYP2D6 P10635 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
OPRM1 P35372 2/20 0.30
OPRK1 P41145 2/20 0.30
OPRL1 P41146 2/20 0.30
OPRD1 P41143 1/20 0.30
TAAR1 Q96RJ0 4/20 0.30
SLC6A2 P23975 2/20 0.30
MAOA P21397 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30
SIGMAR1 Q99720 1/20 0.30
CYP2A6 P11509 1/20 0.30
ADORA2A P29274 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5285392 0.76 TSHR (0.37) ALDH1A1HTTELANEMEN1KMT2A
SCHEMBL5275530 0.72 KDM4E (0.35) ALDH1A1MEN1KMT2AOPRM1OPRL1
SCHEMBL3925565 0.71 GAA (0.41) ALDH1A1HTTKMT2ASMN1; SMN2OPRM1
SCHEMBL2233425 0.71 MAOA (0.32) TAAR1MAOA
SCHEMBL5275494 0.71 OPRM1 (0.32) ALDH1A1OPRM1OPRK1OPRL1TAAR1
SCHEMBL5278439 0.71 TAAR1 (0.35) ALDH1A1HTTELANECYP2D6TAAR1
SCHEMBL5282094 0.70 OPRL1 (0.42) ALDH1A1OPRM1OPRK1OPRL1MAOA
SCHEMBL5279879 0.70 CYP2D6 (0.34) ALDH1A1CYP2D6SMN1; SMN2OPRM1OPRK1
SCHEMBL5279220 0.69 OPRM1 (0.44) ALDH1A1ELANEOPRM1OPRK1OPRL1
SCHEMBL27476300 0.68 TRPA1 (0.37) ALDH1A1TAAR1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1859782-A1 Composition for coloring and/or lightening human hair comprising tetrazoles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed