Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.47 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | TYK2 | P29597 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL529590 | 0.94 | LMNA (0.49) | LMNAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL529348 | 0.89 | SMN1; SMN2 (0.51) | LMNAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL528658 | 0.89 | ALDH1A1 (0.53) | LMNAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL528938 | 0.89 | ALDH1A1 (0.59) | LMNAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL528307 | 0.87 | KMT2A (0.63) | LMNAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL528626 | 0.85 | ALDH1A1 (0.46) | LMNAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL528344 | 0.84 | MAPT (0.56) | LMNAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL528550 | 0.84 | ALDH1A1 (0.55) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL528301 | 0.83 | MAPT (0.48) | LMNAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL528200 | 0.83 | ALDH1A1 (0.55) | LMNAALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | claimed |
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |