Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | GPR27 | Q9NS67 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528292 | 0.93 | TP53 (0.46) | ALDH1A1GAAHTTMAPTNPSR1 | |
| SCHEMBL529590 | 0.91 | LMNA (0.49) | ALDH1A1GAAHTTMAPTNPSR1 | |
| SCHEMBL528511 | 0.89 | KMT2A (0.52) | ALDH1A1HTTMAPTNPSR1SMN1; SMN2 | |
| SCHEMBL528323 | 0.88 | GAA (0.44) | ALDH1A1GAAHTTMAPTNPSR1 | |
| SCHEMBL528340 | 0.88 | FFAR1 (0.51) | ALDH1A1GAAMAPTSMN1; SMN2HPGD | |
| SCHEMBL528672 | 0.87 | SMO (0.46) | ALDH1A1MAPTGPR27SMN1; SMN2HPGD | |
| SCHEMBL528041 | 0.86 | HTT (0.56) | ALDH1A1GAAHTTMAPTNPSR1 | |
| SCHEMBL527889 | 0.86 | ALDH1A1 (0.58) | ALDH1A1GAAHTTMAPTNPSR1 | |
| SCHEMBL528111 | 0.86 | MAPT (0.48) | ALDH1A1HTTMAPTNPSR1SMN1; SMN2 | |
| SCHEMBL528022 | 0.85 | LMNA (0.49) | ALDH1A1HTTMAPTNPSR1GPR27 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |