Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GRK6 | P43250 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | POLQ | O75417 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5281477 | 0.88 | PDGFRB (0.43) | PDGFRBPDGFRAHTTHPGDMEN1 | |
| SCHEMBL5278083 | 0.87 | ALDH1A1 (0.39) | PDGFRBPDGFRANPC1ATMALDH1A1 | |
| SCHEMBL5126198 | 0.86 | ALDH1A1 (0.54) | PDGFRBPDGFRAHTTHPGDMEN1 | |
| SCHEMBL5287033 | 0.85 | LMNA (0.45) | PDGFRBPDGFRAHTTMEN1KMT2A | |
| SCHEMBL5292147 | 0.83 | CYP11B2 (0.41) | HPGDMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL5283181 | 0.83 | ALDH1A1 (0.39) | L3MBTL1NPC1ATMALDH1A1KDM4E | |
| SCHEMBL5281269 | 0.83 | ALDH1A1 (0.41) | PDGFRBPDGFRAHTTL3MBTL1NPC1 | |
| SCHEMBL5278782 | 0.82 | CYP1A2 (0.42) | PDGFRBPDGFRAHTTL3MBTL1NPC1 | |
| SCHEMBL5279567 | 0.79 | ALDH1A1 (0.56) | MEN1KMT2AL3MBTL1NPC1ATM | |
| SCHEMBL5119482 | 0.78 | PDGFRB (0.48) | PDGFRBPDGFRAHTTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1866289-A1 | PYRIMIDINE CARBOXYLIC ACID DERIVATIVES AND USE THEREOF | Bayer HealthCare AG (DE) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006097220-A1 | PYRIMIDINE CARBOXYLIC ACID DERIVATIVES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2006-09-21 | — | — | WO | disclosed |