SCHEMBL528104

SCHEMBL528104

NC(=O)C=CC(CO)(CO)CO

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
TSHR P16473 1/20 0.36
FGFR4 P22455 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11443580 0.79 ALDH1A1 (0.36) ALDH1A1TSHRFGFR4
SCHEMBL617583 0.77 ALDH1A1 (0.35) ALDH1A1TSHRFGFR4
SCHEMBL9703841 0.77 ALDH1A1 (0.35) ALDH1A1TSHRFGFR4
SCHEMBL15711296 0.75 ALDH1A1 (0.33) ALDH1A1TSHRFGFR4
SCHEMBL18043219 0.75 ALDH1A1 (0.33) ALDH1A1TSHRFGFR4
Ethylene Glycol SCHEMBL18065843 0.73 ALDH1A1 (0.32) ALDH1A1TSHRFGFR4
Ethylene Glycol SCHEMBL18065818 0.73 ALDH1A1 (0.32) ALDH1A1TSHRFGFR4
SCHEMBL5606583 0.70
SCHEMBL11779745 0.69 ALDH1A1 (0.42) ALDH1A1TSHRFGFR4
Succinic Acid SCHEMBL3195268 0.69 LMNA (0.41) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3872101-B1 POLYMERIC PARTICLES LIFE TECH AS (NO) 2025-08-20 EP claimed
US-12162987-B2 Silicone hydrogel contact lenses ALCON INC. (CH) 2024-12-10 US claimed
US-20230272127-A1 POLYMERIC PARTICLES LIFE TECHNOLOGIES AS (NO) 2023-08-31 US claimed
EP-3325522-B1 POLYMERIC PARTICLES LIFE TECH AS (NO) 2023-06-28 EP claimed
US-20230108947-A1 POLYMER EXCIPIENTS FOR BIOPHARMACEUTICAL FORMULATIONS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2023-04-06 US claimed
EP-3571234-B1 POLYMERIC PARTICLES LIFE TECH AS (NO) 2021-05-05 EP claimed
US-10836854-B2 Inverse Ugelstad particles SINTEF (NO) 2020-11-17 US claimed
EP-3559091-A1 METHOD OF PREPARING A POLYROTAXANE AND POLYROTAXANE Universität des Saarlandes (DE) 2019-10-30 EP claimed
US-20180215852-A1 Inverse Ugelstad Particles SINTEF (NO) 2018-08-02 US claimed
WO-2018134374-A2 POLYMERIC PARTICLES LIFE TECHNOLOGIES AS (NO) 2018-07-26 WO claimed
WO-2018115238-A1 METHOD OF PREPARING A POLYROTAXANE AND POLYROTAXANE UNIVERSITAET DES SAARLANDES (DE) 2018-06-28 WO claimed
EP-3325522-A1 POLYMERIC PARTICLES Life Technologies AS (NO) 2018-05-30 EP claimed
WO-2017013138-A1 POLYMERIC PARTICLES LIFE TECHNOLOGIES AS (NO) 2017-01-26 WO claimed
EP-3049560-A1 DETECTABLE ARRAYS, SYSTEMS FOR DIAGNOSIS, AND METHODS OF MAKING AND USING THE SAME Entopsis (US) 2016-08-03 EP claimed
WO-2015047958-A1 DETECTABLE ARRAYS, SYSTEMS FOR DIAGNOSIS, AND METHODS OF MAKING AND USING THE SAME ENTOPSIS (US) 2015-04-02 WO claimed
EP-1796737-A2 MICROSPHERES CAPABLE OF BINDING RADIOISOTOPES, OPTIONALLY COMPRISING METALLIC MICROPARTICLES, AS WELL AS METHODS OF USE THEREOF BIOSPHERE MEDICAL, INC. (US) 2007-06-20 EP claimed
WO-2006036269-A2 MICROSPHERES CAPABLE OF BINDING RADIOISOTOPES, OPTIONALLY COMPRISING METALLIC MICROPARTICLES, AND METHODS OF USE THEREOF BIOSPHERE MEDICAL, INC. (US) 2006-04-06 WO claimed
EP-4440643-A2 MEDICAL DEVICE WITH CD31 MIMETIC COATING INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2024-10-09 EP disclosed
US-20030092834-A1 Cellulose copolymers that modify fibers and surfaces and methods of making same FREESLATE, INC. 2003-05-15 US disclosed
WO-2003010268-A1 USE OF COMPOUNDS IN PRODUCTS FOR LAUNDRY APPLICATIONS UNILEVER PLC (GB) 2003-02-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230108947-A1 POLYMER EXCIPIENTS FOR BIOPHARMACEUTICAL FORMULATIONS IAPP, PNLIP, INSRR ALDH1A1 4840/4885TSHR 1677/4885FGFR4 4224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.