SCHEMBL617583

SCHEMBL617583

NC(=O)C=CC(O)(C=CC(N)=O)CO

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
FGFR4 P22455 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL18065843 0.95 ALDH1A1 (0.32) ALDH1A1TSHRFGFR4
Ethylene Glycol SCHEMBL18065818 0.95 ALDH1A1 (0.32) ALDH1A1TSHRFGFR4
SCHEMBL528104 0.77 ALDH1A1 (0.36) ALDH1A1TSHRFGFR4
SCHEMBL11443580 0.77 ALDH1A1 (0.36) ALDH1A1TSHRFGFR4
Ethylene Glycol SCHEMBL1485678 0.73 TSHR (0.36) TSHR
SCHEMBL18043219 0.73 ALDH1A1 (0.33) ALDH1A1TSHRFGFR4
Ethylene Glycol SCHEMBL1271188 0.73 TSHR (0.36) TSHR
Ethylene Glycol SCHEMBL1278023 0.73 TSHR (0.36) TSHR
Ethylene Glycol SCHEMBL1278362 0.73 TSHR (0.36) TSHR
SCHEMBL15711296 0.73 ALDH1A1 (0.33) ALDH1A1TSHRFGFR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2598599-B1 STIMULI-RESPONSIVE HIGH VISCOSITY PILL HALLIBURTON ENERGY SERVICES INC (US) 2015-06-17 EP claimed
WO-2015055652-A1 PROSTHESIS SEAL SYMETIS SA (CH) 2015-04-23 WO claimed
US-20130253087-A1 HYDROGEL FILAMENTS FOR BIOMEDICAL USES MICROVENTION, INC. (US) 2013-09-26 US claimed
US-8470035-B2 Hydrogel filaments for biomedical uses MICROVENTION, INC. (US) 2013-06-25 US claimed
US-8418761-B2 Stimuli-responsive high viscosity pill HALLIBURTON ENERGY SERVICES, INC. (US) 2013-04-16 US claimed
US-20120202263-A1 Bioactive Macromers and Hydrogels and Methods for Producing Same THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2012-08-09 US claimed
US-20110184513-A1 Artificial corneal implant BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY, THE 2011-07-28 US claimed
US-20110033540-A1 POLYMER FORMULATIONS FOR DELIVERY OF BIOACTIVE AGENTS CARBYLAN THERAPEUTICS, INC. 2011-02-10 US claimed
EP-2117513-A2 POLYMER FORMULATIONS FOR DELIVERY OF BIOACTIVE AGENTS Carbylan Biosurgery, Inc. (US) 2009-11-18 EP claimed
WO-2008098019-A2 POLYMER FORMULATIONS FOR DELIVERY OF BIOACTIVE AGENTS CARBYLAN BIOSURGERY, INC. (US) 2008-08-14 WO claimed
EP-1437368-A1 COMPOSITION FOR POLYMERISING IMMOBILISATION OF BIOLOGICAL MOLECULES AND METHOD FOR PRODUCING SAID COMPOSITION INSTITUT MOLEKULYARNOI BIOLOGII IM. V.A.ENGELGARDTA ROSSIISKOI AKADEMII NAUK (RU) 2004-07-14 EP claimed
US-20040053298-A1 Composition for polymerising immobilisation of biological molecules and method for producing said composition UCHREZHDENIE ROSSIISKOI AKADEMII NAUK INSTITUT MOLEKULYARNOI BIOLOGII IM. V.A. ENGELGARDTA RAN (IMB RAN) (RU) 2004-03-18 US claimed
CN-118267537-A Medical hydrogel composition, medical hydrogel, preparation method and application thereof 广州迈普再生医学科技股份有限公司 2024-07-02 CN disclosed
US-11957755-B2 Radiopaque polymers Boston Scientific Medical Device Limited (IE) 2024-04-16 US disclosed
US-11873468-B2 Polymers for the treatment of surfaces HENKEL AG & CO. KGAA (DE) 2024-01-16 US disclosed
EP-3492110-B1 RADIOPAQUE POLYMERS BIOCOMPATIBLES UK LTD (GB) 2023-03-08 EP disclosed
WO-2005047435-A2 CATALYTIC GASIFICATION ITI LIMITED (GB) 2005-05-26 WO disclosed
WO-2004037164-A2 CROSSLINKED COMPOUNDS AND METHODS OF MAKING AND USING THEREOF UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2004-05-06 WO disclosed
EP-1183328-A2 MICROCELLULAR POLYMERS AS CELL GROWTH MEDIA AND NOVEL POLYMERS Protensive Limited (GB) 2002-03-06 EP disclosed
WO-2000034454-A2 MICROCELLULAR POLYMERS AS CELL GROWTH MEDIA AND NOVEL POLYMERS NEWCASTLE UNIVERSITY VENTURES LIMITED (GB) 2000-06-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040053298-A1 Composition for polymerising immobilisation of biological molecules and method for producing said composition PTMS, DNMT3A, PCNA ALDH1A1 3271/4885TSHR 3530/4885FGFR4 2880/4885
US-11957755-B2 Radiopaque polymers RXFP3, RXFP1, DAGLA ALDH1A1 292/4885TSHR 3067/4885FGFR4 3863/4885
US-20110033540-A1 POLYMER FORMULATIONS FOR DELIVERY OF BIOACTIVE AGENTS BMP2, BMP6, BMP4 ALDH1A1 3390/4885TSHR 4548/4885FGFR4 651/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.