SCHEMBL5282287

SCHEMBL5282287

O=C(O)C(=C(Br)Br)C(Br)C(Br)(Br)Oc1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ALOX15 P16050 1/20 0.32
EDNRB P24530 1/20 0.32
EDNRA P25101 1/20 0.32
F2 P00734 1/20 0.31
LMNA P02545 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
PPARG P37231 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6046998 0.69 CA4 (0.42) CES2CES1LMNAALDH1A1
SCHEMBL6047010 0.67 CES2 (0.59) CES2CES1L3MBTL1LMNA
SCHEMBL351499 0.67 THRB (0.45) CES2CES1ATML3MBTL1ALOX15
SCHEMBL28100996 0.66 CA4 (0.44) ATML3MBTL1EDNRBEDNRALMNA
SCHEMBL3291856 0.66 ELANE (0.43) ATML3MBTL1EDNRBEDNRAKDM4E
SCHEMBL11032500 0.64
SCHEMBL5490232 0.64 TGM2 (0.44) LMNAALDH1A1
SCHEMBL10895175 0.63 CA4 (0.32)
SCHEMBL9202234 0.63 LTA4H (0.41) ALOX15LMNAALDH1A1PPARG
SCHEMBL406332 0.62 PPARG (0.36) L3MBTL1ALOX15LMNAKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007007332-A1 TRIBROMONEOPENTYL (METH)ACRYLATE BASED COPOLYMERS AND LENSES MADE THEREFROM H.P.O.P - HIGH PERFORMANCE OPTICAL POLYMERS LTD. (IL) 2007-01-18 WO disclosed