Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528261 | 0.93 | MAPK1 (0.58) | L3MBTL1MAPTALDH1A1MAPK1KDM4E | |
| SCHEMBL528632 | 0.86 | ALDH1A1 (0.51) | SMN1; SMN2L3MBTL1MAPTALDH1A1MAPK1 | |
| SCHEMBL529458 | 0.86 | MAPT (0.52) | NPC1SMN1; SMN2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL528847 | 0.86 | MEN1 (0.55) | SMN1; SMN2L3MBTL1MAPTALDH1A1KDM4E | |
| SCHEMBL528474 | 0.85 | KCNK3 (0.53) | NPC1RAB9AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL528567 | 0.84 | KCNK3 (0.54) | L3MBTL1MAPTALDH1A1MAPK1KDM4E | |
| SCHEMBL528522 | 0.83 | MEN1 (0.52) | NPC1RAB9ASMN1; SMN2TP53L3MBTL1 | |
| SCHEMBL528468 | 0.83 | L3MBTL1 (0.57) | NPC1RAB9ASMN1; SMN2TP53L3MBTL1 | |
| SCHEMBL528589 | 0.83 | MEN1 (0.52) | SMN1; SMN2L3MBTL1MAPTALDH1A1KDM4E | |
| SCHEMBL529102 | 0.83 | MAPT (0.55) | SMN1; SMN2MAPTALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |