Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MLYCD | O95822 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL529361 | 0.91 | ALDH1A1 (0.50) | MAPTHTTKDM4EALDH1A1HPGD | |
| SCHEMBL528277 | 0.90 | MAPT (0.62) | MAPTHTTKDM4EPOLBALDH1A1 | |
| SCHEMBL527892 | 0.88 | MAPT (0.73) | MAPTHTTKDM4EPOLBALDH1A1 | |
| SCHEMBL528675 | 0.87 | MAPT (0.51) | MAPTHTTKDM4EALDH1A1HPGD | |
| SCHEMBL528229 | 0.87 | MAPT (0.62) | MAPTHTTKDM4EPOLBALDH1A1 | |
| SCHEMBL528853 | 0.85 | MAPT (0.75) | MAPTHTTKDM4EPOLBALDH1A1 | |
| SCHEMBL528566 | 0.85 | MAPT (0.59) | MAPTHTTKDM4EPOLBALDH1A1 | |
| SCHEMBL528269 | 0.84 | NPSR1 (0.53) | MAPTHTTKDM4EALDH1A1HPGD | |
| SCHEMBL528274 | 0.84 | L3MBTL1 (0.47) | MAPTHTTKDM4EPOLBALDH1A1 | |
| SCHEMBL528351 | 0.83 | MAPT (0.48) | MAPTHTTKDM4EPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |