Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MRGPRX1 | Q96LB2 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TSPO | P30536 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL529288 | 0.91 | MAPT (0.58) | ALDH1A1GAAMAPTKDM4EHPGD | |
| SCHEMBL528865 | 0.88 | ALDH1A1 (0.54) | ALDH1A1GAAMAPTKDM4EHPGD | |
| SCHEMBL528045 | 0.88 | MAPT (0.61) | ALDH1A1GAAMAPTKDM4EHPGD | |
| SCHEMBL528675 | 0.88 | MAPT (0.51) | ALDH1A1MAPTKDM4EHPGDHTT | |
| SCHEMBL528515 | 0.86 | ALDH1A1 (0.52) | ALDH1A1GAAMAPTKDM4EHPGD | |
| SCHEMBL528552 | 0.86 | KDM4E (0.64) | ALDH1A1GAAMAPTKDM4EHPGD | |
| SCHEMBL528572 | 0.84 | RXFP1 (0.48) | ALDH1A1MAPTMRGPRX1RAB9ATSPO | |
| SCHEMBL528269 | 0.83 | NPSR1 (0.53) | ALDH1A1MAPTKDM4EHPGDHTT | |
| SCHEMBL528277 | 0.82 | MAPT (0.62) | ALDH1A1GAAMAPTKDM4EHPGD | |
| SCHEMBL528351 | 0.81 | MAPT (0.48) | ALDH1A1MAPTKDM4EHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |