Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528115 | 0.85 | ALDH1A1 (0.39) | KMT2AMEN1ALDH1A1L3MBTL1HDAC1 | |
| SCHEMBL528451 | 0.85 | ALDH1A1 (0.39) | KMT2AMEN1ALDH1A1L3MBTL1HDAC1 | |
| SCHEMBL528312 | 0.84 | KMT2A (0.47) | KMT2AMEN1ALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL528313 | 0.84 | KMT2A (0.47) | KMT2AMEN1ALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL531077 | 0.84 | GPR139 (0.40) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL531078 | 0.84 | GPR139 (0.40) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL528905 | 0.82 | ALDH1A1 (0.37) | KMT2AMEN1ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL528906 | 0.82 | ALDH1A1 (0.37) | KMT2AMEN1ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL528033 | 0.81 | MMP2 (0.44) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL528034 | 0.81 | MMP2 (0.44) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598493-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012014114-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |