Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528851 | 0.93 | RXFP1 (0.46) | MAPTRXFP1POLBTP53ALDH1A1 | |
| SCHEMBL528697 | 0.91 | MAPT (0.42) | OXTRMAPTSMN1; SMN2RXFP1TP53 | |
| SCHEMBL528332 | 0.90 | ALDH1A1 (0.51) | OXTRMAPTSMN1; SMN2POLBTP53 | |
| SCHEMBL527903 | 0.89 | MAPT (0.52) | OXTRMAPTSMN1; SMN2POLBTP53 | |
| SCHEMBL529354 | 0.86 | MAPT (0.55) | OXTRMAPTSMN1; SMN2POLBKDM4E | |
| SCHEMBL528225 | 0.85 | MAPT (0.46) | OXTRTHRBMAPTSMN1; SMN2POLB | |
| SCHEMBL529284 | 0.84 | ALDH1A1 (0.56) | THRBMAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL528468 | 0.83 | L3MBTL1 (0.57) | THRBMAPTSMN1; SMN2POLBTP53 | |
| SCHEMBL528514 | 0.82 | L3MBTL1 (0.49) | THRBMAPTSMN1; SMN2RXFP1POLB | |
| SCHEMBL528549 | 0.82 | MAPT (0.56) | OXTRMAPTSMN1; SMN2TP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |