Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | OXTR | P30559 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528384 | 0.89 | OXTR (0.44) | MAPTSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL528851 | 0.88 | RXFP1 (0.46) | MAPTRAB9ATP53KMT2AMEN1 | |
| SCHEMBL528697 | 0.84 | MAPT (0.42) | MAPTSMN1; SMN2LMNATP53KMT2A | |
| SCHEMBL528332 | 0.83 | ALDH1A1 (0.51) | MAPTSMN1; SMN2NPC1LMNATP53 | |
| SCHEMBL529051 | 0.83 | MAPT (0.71) | MAPTSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL529730 | 0.82 | MAPT (0.58) | MAPTSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL529397 | 0.81 | MAPT (0.57) | MAPTSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL529592 | 0.80 | MAPT (0.55) | MAPTSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL529438 | 0.79 | MAPT (0.54) | MAPTSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL528985 | 0.79 | MAPT (0.54) | MAPTSMN1; SMN2NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |