Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.54 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RORB | Q92753 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6229196 | 0.80 | GABRA1 (0.67) | BCAT2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL5299783 | 0.76 | PKM (0.47) | ALDH1A1HPGDLMNAL3MBTL1NPC1 | |
| SCHEMBL3256879 | 0.76 | BCAT2 (0.57) | BCAT2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL8709909 | 0.75 | SLC6A3 (0.55) | BCAT2KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2980845 | 0.74 | BCAT2 (0.68) | BCAT2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL9121778 | 0.73 | BCAT2 (0.72) | BCAT2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL1670982 | 0.73 | BCAT2 (0.72) | BCAT2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL28542886 | 0.72 | BCAT2 (0.55) | BCAT2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL4445671 | 0.71 | BCAT2 (1.00) | BCAT2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL30952652 | 0.70 | BCAT2 (0.62) | BCAT2GABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |