Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.45 |
| ▸ | SHBG | P04278 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31225690 | 0.85 | TAAR1 (0.45) | SMN1; SMN2MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL5294704 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2MEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL31225781 | 0.83 | AKR1B1 (0.52) | SMN1; SMN2MAPTL3MBTL1TDP1ATM | |
| SCHEMBL22714328 | 0.79 | SMN1; SMN2 (0.51) | SMN1; SMN2CTBP2SHBGMEN1KMT2A | |
| SCHEMBL10964197 | 0.78 | ALDH1A1 (0.39) | SMN1; SMN2L3MBTL1TDP1NPC1RAB9A | |
| SCHEMBL28267690 | 0.78 | CTBP2 (0.53) | SMN1; SMN2CTBP2SHBGMEN1KMT2A | |
| SCHEMBL6937307 | 0.77 | SMN1; SMN2 (0.67) | SMN1; SMN2MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL30522283 | 0.77 | CTBP2 (0.51) | CTBP2SHBGMEN1KMT2AMAPT | |
| SCHEMBL265432 | 0.77 | CTBP2 (0.51) | CTBP2SHBGMEN1KMT2AMAPT | |
| SCHEMBL5287421 | 0.76 | MMP2 (0.49) | SMN1; SMN2KMT2AL3MBTL1ATMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | CLSPN, LMAN2, RPN2 | SMN1; SMN2 3894/4885CTBP2 779/4885SHBG 4779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.